Investors / United States / 25madison
25madison
Venture capital · New York, NY, United States · North America
25madison is an AI transformation investment platform that incubates and invests in AI-native software and tech-enabled businesses, and acquires and transforms lower-middle market businesses with applied AI. It also operates a venture studio and, through a partnership with LifePoint Health, a healthtech venture studio called 25m Health.
Invests inHealthcare & Biotech
In its own wordsapplied aihealthtechtech-enabled serviceslegacy industriesbuyoutsincubation
Your fit with 25madison
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See how your round matches what it backs, point by point.
Or find every investor that fits25madison lists 12 checked portfolio companies on its own site and is named in 4 funding rounds. Its most frequent entry is Seed, 100% of the companies with a known first round. Its largest themes are Healthcare & Biotech (39%), Fintech (11%) and AI & Machine Learning (11%). 100% of its companies are based in United States. It invests most often alongside Unusual Ventures, 1843 Capital and Able Partners.
Counts come from funding rounds that name 25madison, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not 25madison's whole history. Rounds on record name 4 companies; its own site lists 12. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 100% |
| Series A | 0% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 1 | 0 |
| '26 | 3 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 30th | 12 companies |
| Recent activity | 76th | 3 rounds in 12 months |
| Early stage | 100th | 100% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 72th | 39% in its largest sector |
| Reach | 20th | 1 country |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 39% | 15% |
| Fintech | 11% | 12% |
| AI & Machine Learning | 11% | 18% |
| Real Estate & Construction | 6% | 3% |
| E-commerce & Marketplaces | 6% | 6% |
| Cybersecurity | 6% | 4% |
| Consumer | 6% | 3% |
| Industrial & Manufacturing | 6% | 7% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Unusual Ventures | 2 |
| 1843 Capital | 1 |
| Able Partners | 1 |
| Actions Capital | 1 |
| Advance Venture Partners | 1 |
| AnD Ventures | 1 |
| Angelini Ventures | 1 |
| Archetype | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers12100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with Unusual Ventures
Compare 25madison head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Funds
from public registers and its siteRecent portfolio activity
when companies last raised with 25madison| Date | Company | Stage |
|---|---|---|
| 23 Jun 2026 | Seed | |
| 2 Apr 2026 | Seed | |
| 22 Oct 2025 | Seed |
Round details for 25madison
Amounts, full round histories and every co-investor in 25madison's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
12 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Clearpol empowers post-acute and long-term care providers to navigate complexities with ease using AI-powered solutions. | Healthcare & Biotech | Portfolio page | ||
| The company allows users to shop, earn 10% back, and resell luxury fashion items through their platform. | E-commerce & MarketplacesFintech | Portfolio page | ||
| FlyteHealth provides a clinically-proven treatment for weight loss and cardiometabolic care | Healthcare & Biotech | Portfolio page | ||
| Handspring Health provides therapy for children and young adults with various mental health challenges | Healthcare & Biotech | Portfolio page | ||
| Hut 8 develops and operates an integrated portfolio of power, digital infrastructure, and compute assets purpose-built to fuel the world's most transformative technologies. | EducationHealthcare & Biotech | Portfolio page | ||
| Midi provides virtual healthcare services for women, including insurance-covered care and treatment plans for various symptoms and health issues | Healthcare & Biotech | Portfolio page | ||
| Ladder Health provides virtual pediatric developmental therapy, including speech, occupational, physical, and feeding therapy, for children | Healthcare & Biotech | Jun 2026Seed | Funding round | |
| Miravoice automates phone surveys and interviews using AI-powered voice interviews | AI & Machine LearningConsumer | Apr 2026Seed | Funding round | |
| Paxton brings the case files and legal research into one workspace for litigation teams. | Legal & Compliance | Portfolio page | ||
| Silkline provides a platform for supply chain orchestration for advanced manufacturing | AI & Machine LearningIndustrial & Manufacturing | Oct 2025Seed | Funding round | |
| Truehold helps homeowners and investors access and utilize the equity in their properties through various financial solutions and services. | Real Estate & ConstructionFintech | Portfolio page | ||
| Vinesight tracks how stories form, spread, and reach the mainstream, in time to act and at the scale of the internet. | Healthcare & BiotechCybersecurity | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- 25madison.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 22 Oct 2025
- Companies checked
- 12
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
Get 25madison's profile as data
Pull 25madison's portfolio, co-investors and changes through one API key or MCP, open every portfolio row, compare it with other firms, and get an email when it adds a company or files a fund.
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- Full listsEvery portfolio row and two-firm overlap
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- AlertsFollow 5 investors for portfolio and fund changes
$ curl -H "X-API-Key: YOUR_KEY" \
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