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Investors / United Kingdom / 4BIO Capital

4BIO Capital

Venture capital · London, United Kingdom · Europe

4biocapital.com

4BIO Capital is a London-based venture capital firm focused solely on the advanced therapies sector. It invests in, supports and grows early stage companies developing treatments in areas of high unmet medical need.

Invests inHealthcare & Biotech

In its own wordsadvanced therapiescell therapygene therapyrna therapeuticsmicrobiomelife sciences

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7portfolio companies
8funding rounds on record5 led
7rounds, last 12 months
$20M to $100Mtypical round it comes in at
Series Amost frequent entry
EuVECA fund registered with FCA, no longer activelatest fund

4BIO Capital lists 7 checked portfolio companies on its own site and is named in 8 funding rounds, 5 of them as lead. Its most frequent entry is Series A, 50% of the companies with a known first round. Its largest theme is Healthcare & Biotech (100%). 43% of its companies are based in United Kingdom. It invests most often alongside IQ Capital, Kerna Ventures and Mission BioCapital.

Counts come from funding rounds that name 4BIO Capital, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.

Entry stage

share of companies by the stage of its first round
Show as a table
Share of companies by the stage of the firm's first round
Value
Pre-seed0%
Seed38%
Series A50%
Series B13%
Growth0%

Activity by year

rounds it joined, last 10 years
Show as a table
Funding rounds per year
TotalRounds it led
'1700
'1800
'1900
'2000
'2100
'2200
'2300
'2400
'2510
'2675

Investor profile

percentile among all firms
Portfolio size: 7 companiesRecent activity: 7 rounds in 12 monthsEarly stage: 38% of entries at pre-seed or seedEvidence: 0% of companies confirmed by a roundSector focus: 100% in its largest sectorReach: 4 countriesPortfolio size12th pctRecent activity91th pctEarly stage65th pctEvidence52th pctSector focus100th pctReach70th pct
This firmMedian of all firms
Show as a table
4BIO Capital compared with all firms
MeasurePercentile of all firmsValue
Portfolio size12th7 companies
Recent activity91th7 rounds in 12 months
Early stage65th38% of entries at pre-seed or seed
Evidence52th0% of companies confirmed by a round
Sector focus100th100% in its largest sector
Reach70th4 countries

Invests most often with

firms sharing its portfolio companies
Show as a table
Co-investors
Share
IQ Capital2
Kerna Ventures2
Mission BioCapital2
AIN Ventures1
Abingworth1
Angelini Ventures1
BrightEdge1
British Business Bank1

All co-investors

Its portfolio companies

where they are based, and what their own sites show

Site status

  • Site answers7100%
  • No longer answers00%
  • Points to another company00%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
Healthcare & Biotech100%15%

Compare 4BIO Capital head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Funds

from public registers and its site
4Bio Ventures II LPEuVECA fund registered with FCA, no longer active, ESMA register

Recent portfolio activity

when companies last raised with 4BIO Capital
DateCompanyStage
10 Nov 2026Oyster Therapeuticsoyster-tx.comSeries A Led
16 Oct 2026Estuary Bioestuarybio.comSeries A
13 Oct 2026UndecimalBioundecimalbio.comSeed Led
29 Sept 2026AptaDiraptadir.comSeed Led
8 Sept 2026Cloverleaf Biocloverleafbio.comSeed Led
5 May 2026Cytospirecytospire.comSeries A Led
6 Oct 2025Trogenixtrogenixbio.comSeries A

Round details for 4BIO Capital

Amounts, full round histories and every co-investor in 4BIO Capital's rounds are on Fundup AI. VCinfo covers investors and their portfolios.

See rounds on Fundup AI →

Portfolio

7 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
AptaDiraptadir.com · ItalyAptaDir develops RNA-based therapeutics to reprogram DNA methylation in disease conditions
Healthcare & Biotech
Sept 2026SeedFunding round
Cloverleaf Biocloverleafbio.com · United StatesThe company is developing a new class of RNA therapeutics to revolutionize cancer therapy.
Healthcare & Biotech
Sept 2026SeedFunding round
Cytospirecytospire.com · United KingdomCytospire Therapeutics develops next generation immune cell engagers, including multispecific antibodies and gamma delta T cell engagers, for cancer therapies.
Healthcare & Biotech
May 2026Series AFunding round
Estuary Bioestuarybio.com · United StatesEstuary Bio is developing gene therapies to treat autosomal dominant polycystic kidney disease (ADPKD)
Healthcare & Biotech
Oct 2026Series AFunding round
Oyster Therapeuticsoyster-tx.com · United KingdomOyster Therapeutics develops smaller protein degrader therapeutics to reach new biological targets and bigger populations, starting with neurodegenerative disease.
Healthcare & Biotech
Nov 2026Series AFunding round
Trogenixtrogenixbio.com · United KingdomTrogenix develops precision cancer treatments using gene therapy
Healthcare & Biotech
Oct 2025Series AFunding round
UndecimalBioundecimalbio.com · IsraelUndecimalBio pairs massive scale combinatorial chemistry with transformer-based AI to guide siRNA therapeutics into the tissues that need them.
Healthcare & Biotech
Oct 2026SeedFunding round

About this data

site last read 5 Nov 2026
The homepage of 4BIO Capital, as last read
4biocapital.com as VCinfo last read it
Site
4biocapital.com
Last read
5 Nov 2026
Watching since
6 Nov 2026
Rounds since
6 Oct 2025
Companies checked
7

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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