Investors / United States / Breakout Ventures
Breakout Ventures
Venture capital · San Francisco, CA, United States · North America
Breakout Ventures is a venture capital firm that invests early in science-driven companies, often leading deals. It focuses on founders applying technology, including AI, to biological and chemical data and other scientific domains.
Invests inHealthcare & Biotech
In its own wordssciencebiotechaidrug discoveryclimatecomputational biology
Your fit with Breakout Ventures
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsBreakout Ventures lists 27 checked portfolio companies on its own site and is named in 2 funding rounds, 1 of them as lead. Its most frequent entry is Seed, 100% of the companies with a known first round. Its largest themes are Healthcare & Biotech (53%), AI & Machine Learning (14%) and Industrial & Manufacturing (11%). 95% of its companies are based in United States. It invests most often alongside KdT Ventures, IndieBio and Refactor Capital.
Counts come from funding rounds that name Breakout Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Breakout Ventures' whole history. Rounds on record name 2 companies; its own site lists 27. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 100% |
| Series A | 0% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 0 | 0 |
| '26 | 2 | 1 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 64th | 27 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 100th | 100% of entries at pre-seed or seed |
| Evidence | 71th | 7% of companies confirmed by a round |
| Sector focus | 86th | 53% in its largest sector |
| Reach | 42th | 2 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 53% | 15% |
| AI & Machine Learning | 14% | 18% |
| Industrial & Manufacturing | 11% | 7% |
| Space & Defense | 6% | 3% |
| Food & Agriculture | 6% | 3% |
| Robotics & Hardware | 3% | 1% |
| Consumer | 3% | 3% |
| Mobility & Logistics | 3% | 1% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| KdT Ventures | 4 |
| IndieBio | 3 |
| Refactor Capital | 3 |
| SOSV | 3 |
| Capital Factory | 2 |
| Cavallo Ventures | 2 |
| DCVC | 2 |
| Dolby Family Ventures | 2 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers2593%
- No longer answers00%
- Points to another company27%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherCompare Breakout Ventures head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Breakout Ventures| Date | Company | Stage |
|---|---|---|
| 26 Aug 2026 | Seed | |
| 24 Jun 2026 | Seed Led |
Round details for Breakout Ventures
Amounts, full round histories and every co-investor in Breakout Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
27 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| A-Alpha Bio harnesses synthetic biology and machine learning to precisely engineer high-impact medicines | Healthcare & Biotech | Portfolio page | ||
| AquaPoro manufactures pure drinking water directly from the air for residential and industrial applications | Industrial & ManufacturingConsumer | Jun 2026Seed | Page + round | |
| Portfolio page | ||||
| CellChorus develops and applies a single-cell analysis technology to understand how individual cells move, activate, interact, kill and survive | Healthcare & Biotech | Portfolio page | ||
| Checkerspot creates specialized lipids from fermentation ingredients inspired by nature | Food & AgricultureHealthcare & Biotech | Portfolio page | ||
| Constellation builds foundation models of human state to understand brains, bodies, and environments | AI & Machine LearningHealthcare & Biotech | Portfolio page | ||
| Copernic Catalysts designs novel catalysts for ammonia and other bulk chemicals using AI | Industrial & Manufacturing | Portfolio page | ||
| Cytovale develops a medical device for the diagnosis of sepsis | Healthcare & Biotech | Portfolio page | ||
| Ecovative grows food and materials using mycelium on plant feedstock | Food & AgricultureMobility & Logistics | Portfolio page | ||
| The company develops a platform for RNA therapeutics manufacturing. | Healthcare & Biotech | Portfolio page | ||
| Epana Bio treats autoimmune disease by targeting its cellular origin and using genomics and AI to build medicines | Healthcare & Biotech | Portfolio page | ||
| Portfolio page | ||||
| General Sense develops a platform that utilizes dogs' sense of smell to detect various molecular signatures for applications in security, healthcare, and agriculture. | Healthcare & BiotechAI & Machine Learning | Portfolio page | ||
| Immusoft engineers B cells as biofactories for therapeutic protein delivery | Healthcare & Biotech | Portfolio page | ||
| Modern Meadow produces biofabricated leather | Legal & ComplianceAI & Machine Learning | Portfolio page | ||
| Noetik is an AI-native biotechnology company that leverages advanced machine learning methods to discover and develop cancer therapies. | Healthcare & Biotech | Portfolio page | ||
| Parallel Bio reimagines the entire drug discovery process from the ground up, creating a system that charts the map of human biology | Healthcare & Biotech | Portfolio page | ||
| Passkey Therapeutics develops and maps synergistic drug combinations to treat various diseases by utilizing its Locksmith platform | Healthcare & Biotech | Portfolio page | ||
| Phantom Neuro creates a muscle-computer interface for controlling robotic systems | Healthcare & BiotechRobotics & Hardware | Portfolio page | ||
Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- breakout.vc
- Last read
- 5 Nov 2026
- Watching since
- 6 Nov 2026
- Rounds since
- 24 Jun 2026
- Companies checked
- 27
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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