Investors / United States / Define Ventures
Define Ventures
Venture capital · San Francisco, CA, United States · North America
Define Ventures is a venture capital firm focused on early-stage health tech companies. It reports $800 million in assets under management across six funds and provides portfolio support in go-to-market, talent, and capital raising.
Invests inHealthcare & BiotechAI & Machine Learning
In its own wordshealth techdigital healthvalue-based careenterprisedirect-to-consumerai
Your fit with Define Ventures
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See how your round matches what it backs, point by point.
Or find every investor that fitsDefine Ventures lists 9 checked portfolio companies on its own site and is named in 9 funding rounds, 4 of them as lead. Its most frequent entry is Series B, 44% of the companies with a known first round. Its largest themes are Healthcare & Biotech (73%) and AI & Machine Learning (27%). 100% of its companies are based in United States. It invests most often alongside Y Combinator, Calm/Storm Ventures and Peak XV Partners.
Counts come from funding rounds that name Define Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 22% |
| Series A | 33% |
| Series B | 44% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 2 | 1 |
| '26 | 7 | 3 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 19th | 9 companies |
| Recent activity | 91th | 7 rounds in 12 months |
| Early stage | 58th | 22% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 92th | 73% in its largest sector |
| Reach | 19th | 1 country |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Y Combinator | 4 |
| Calm/Storm Ventures | 2 |
| Peak XV Partners | 2 |
| Spider Capital | 2 |
| 7wire Ventures | 1 |
| Accel | 1 |
| Catalio Capital Management | 1 |
| Cigna Ventures | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers9100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 73% | 15% |
| AI & Machine Learning | 27% | 18% |
Co-investor network
who it backs companies with, and who they back togetherCompare Define Ventures head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Define Ventures| Date | Company | Stage |
|---|---|---|
| 13 Oct 2026 | Series A Led | |
| 25 Sept 2026 | Seed | |
| 14 Sept 2026 | Series A | |
| 26 Aug 2026 | Series B Led | |
| 19 May 2026 | Seed | |
| 12 May 2026 | Series B Led | |
| 9 Apr 2026 | Series B | |
| 21 Oct 2025 | Series B |
Round details for Define Ventures
Amounts, full round histories and every co-investor in Define Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
9 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Arintra develops an AI-driven platform for revenue assurance in the healthcare industry, specifically for medical coding and revenue cycle management. | Healthcare & BiotechAI & Machine Learning | Aug 2026Series B | Funding round | |
| Atmos Clinic provides healthcare services, including virtual doctor visits and a card that pays for care, to teams of employees | Healthcare & Biotech | Sept 2026Seed | Funding round | |
| Blank Bio develops models to interpret RNA-seq data to help pharmaceutical companies make better clinical development decisions | Healthcare & Biotech | May 2026Seed | Funding round | |
| Foundation Health provides a platform designed to automate and streamline pharmacy workflows and patient care | Healthcare & Biotech | Oct 2025Series A | Funding round | |
| Hyro provides a care communications platform for healthcare providers to manage patient interactions and workflows. | Healthcare & BiotechAI & Machine Learning | Oct 2025Series B | Funding round | |
| 9amHealth provides specialized care for weight loss, diabetes, and heart health | Healthcare & Biotech | May 2026Series B | Funding round | |
| Luminai automates complex tasks for health systems so their teams can focus on outcomes, not obstacles. | Healthcare & Biotech | Apr 2026Series B | Funding round | |
| Nuance Labs is building a human foundation model with emotional intelligence for face-to-face AI interaction | AI & Machine Learning | Sept 2026Series A | Funding round | |
| Readily provides an AI-native compliance platform for healthcare, helping with regulatory requirements and compliance management. | Healthcare & Biotech | Oct 2026Series A | Funding round |
About this data
site last read 8 Nov 2026- Site
- definevc.com
- Last read
- 8 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 1 Oct 2025
- Companies checked
- 9
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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