Investors / United States / Difference Partners
Difference Partners
Venture capital · New York, NY, United States · North America
Difference Partners is an investment firm that backs technology companies. It focuses on companies whose products improve the lives of people who learn and think differently.
Invests inHealthcare & BiotechEducation
In its own wordseducationlearning differencesneurodiversitytechnology
Your fit with Difference Partners
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsDifference Partners lists 32 checked portfolio companies on its own site and is named in 4 funding rounds. Its most frequent entry is Seed, 50% of the companies with a known first round. Its largest themes are Healthcare & Biotech (44%), Education (23%) and AI & Machine Learning (10%). 100% of its companies are based in United States. It invests most often alongside Autism Impact Fund, NewSchools Venture Fund and Andreessen Horowitz.
Counts come from funding rounds that name Difference Partners, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Difference Partners' whole history. Rounds on record name 4 companies; its own site lists 32. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundDifference Partners does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 50% |
| Series A | 50% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 1 | 0 |
| '24 | 0 | 0 |
| '25 | 1 | 0 |
| '26 | 2 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 70th | 32 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 73th | 50% of entries at pre-seed or seed |
| Evidence | 75th | 9% of companies confirmed by a round |
| Sector focus | 78th | 44% in its largest sector |
| Reach | 19th | 1 country |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 44% | 15% |
| Education | 23% | 7% |
| AI & Machine Learning | 10% | 18% |
| Fintech | 6% | 12% |
| Consumer | 6% | 3% |
| Enterprise Software | 4% | 8% |
| Media & Entertainment | 2% | 4% |
| E-commerce & Marketplaces | 2% | 6% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Autism Impact Fund | 3 |
| NewSchools Venture Fund | 3 |
| Andreessen Horowitz | 2 |
| Enable Ventures | 2 |
| Entrepreneurs Roundtable Accelerator | 2 |
| K Street Capital | 2 |
| Operator Partners | 2 |
| ACME Capital | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers3197%
- No longer answers00%
- Points to another company13%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with Autism Impact Fund
Compare Difference Partners head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Difference Partners| Date | Company | Stage |
|---|---|---|
| 21 Aug 2026 | Series A | |
| 24 Jun 2026 | Seed | |
| 6 Oct 2025 | Seed | |
| 9 Feb 2023 | Series A |
Round details for Difference Partners
Amounts, full round histories and every co-investor in Difference Partners' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
32 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Agave Health provides ADHD diagnosis, coaching, and therapy services for adults, covered by insurance. | Healthcare & Biotech | Portfolio page | ||
| Camber provides revenue cycle management and billing software for specialty healthcare care providers | Healthcare & BiotechFintech | Portfolio page | ||
EducationHealthcare & Biotech | Portfolio page | |||
| Cephable provides an on-device AI productivity assistant that helps users control, create, and automate tasks on their computer without sending data to the cloud. | AI & Machine LearningEnterprise Software | Portfolio page | ||
| Daivergent provides work, life, and social skills training for people with disabilities. | EducationHealthcare & Biotech | Portfolio page | ||
| Deon Health is a specialty managed care organization that serves people with intellectual and developmental disabilities | Healthcare & Biotech | Aug 2026Series A | Page + round | |
| Eleplan provides an operating system for family caregivers to manage care records, routines, and teams in one plan | Healthcare & Biotech | Portfolio page | ||
| The company provides virtual autism support and ABA therapy to families. | Healthcare & Biotech | Portfolio page | ||
| Architect Health provides a platform to find, evaluate, and manage healthcare vendors using AI-powered tools. | Healthcare & Biotech | Portfolio page | ||
| Benny provides a platform to streamline SSDI/SSI applications for disability advocates and their clients | Healthcare & BiotechFintech | Portfolio page | ||
| Goally develops and sells a tablet for kids with curated learning apps and limited stimulation | EducationConsumer | Portfolio page | ||
| Valence AI helps companies understand how their customers feel through emotion AI for voice analysis | AI & Machine LearningEnterprise Software | Jun 2026Seed | Funding round | |
| Hipp Health provides practice management software for healthcare providers | Healthcare & Biotech | Oct 2025Seed | Page + round | |
| The company provides a collaborative platform for K12 teams to streamline IEPs, 504s, MTSS, and GT plans | EducationEducation | Portfolio page | ||
| Inclusively provides a workforce intelligence platform to help employees find and use support and give benefits leaders and brokers real-time visibility into employee needs | Human ResourcesAI & Machine Learning | Portfolio page | ||
| Intellispark offers a platform to help schools address student support issues and promote student safety and academic achievement | EducationEducation | Portfolio page | ||
| Joshin connects employees, families, caregivers, and managers with expert coaches, therapists, and service providers, offering continuous support and care for all aspects of life. | Healthcare & Biotech | Portfolio page | ||
| Kinspire provides guidance and support to parents of children with various developmental and behavioral challenges | Healthcare & Biotech | Portfolio page | ||
| Fable helps teams uncover barriers with feedback from real users with disabilities to improve accessibility and usability of digital products | Media & EntertainmentE-commerce & Marketplaces | Portfolio page | ||
| Marker develops and provides a clinical assessment platform for students | Healthcare & Biotech | Feb 2023Series A | Page + round |
About this data
site last read 5 Nov 2026- Site
- differencepartners.com
- Last read
- 5 Nov 2026
- Watching since
- 6 Nov 2026
- Rounds since
- 9 Feb 2023
- Companies checked
- 32
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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