Investors / United States / Fifty Years
Fifty Years
Venture capital · San Francisco, CA, United States · North America
Fifty Years is a pre-seed and seed focused venture capital firm that backs founders using technology to solve the world's biggest problems. It also runs 5050, a free 16-week program helping scientists and engineers become entrepreneurs and start deep tech startups.
Invests inHealthcare & Biotech
In its own wordsdeep techclimatehealthcarebioengineeringenergyai
Your fit with Fifty Years
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsFifty Years lists 77 checked portfolio companies on its own site and is named in 10 funding rounds, 1 of them as lead. Its most frequent entry is Seed, 50% of the companies with a known first round. Its largest themes are Healthcare & Biotech (40%), AI & Machine Learning (12%) and Education (10%). 92% of its companies are based in United States. It invests most often alongside Y Combinator, Metaplanet and DCVC.
Counts come from funding rounds that name Fifty Years, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Fifty Years' whole history. Rounds on record name 10 companies; its own site lists 77. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 50% |
| Series A | 20% |
| Series B | 30% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 1 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 2 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 3 | 1 |
| '26 | 4 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 92th | 77 companies |
| Recent activity | 86th | 5 rounds in 12 months |
| Early stage | 73th | 50% of entries at pre-seed or seed |
| Evidence | 68th | 6% of companies confirmed by a round |
| Sector focus | 74th | 40% in its largest sector |
| Reach | 78th | 5 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 40% | 15% |
| AI & Machine Learning | 12% | 18% |
| Education | 10% | 7% |
| Industrial & Manufacturing | 10% | 7% |
| Space & Defense | 6% | 3% |
| Fintech | 6% | 12% |
| Food & Agriculture | 5% | 3% |
| Cybersecurity | 5% | 4% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Y Combinator | 32 |
| Metaplanet | 9 |
| DCVC | 6 |
| Garage Capital | 6 |
| Refactor Capital | 6 |
| Soma Capital | 6 |
| Liquid 2 Ventures | 5 |
| Lowercarbon Capital | 5 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers7597%
- No longer answers00%
- Points to another company23%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherCompare Fifty Years head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Fifty Years| Date | Company | Stage |
|---|---|---|
| 6 Oct 2026 | Series B | |
| 1 Sept 2026 | Series A | |
| 4 Feb 2026 | Seed | |
| 16 Jan 2026 | Seed | |
| 19 Nov 2025 | Seed Led | |
| 17 Nov 2025 | Series B | |
| 22 Mar 2025 | Seed | |
| 21 Oct 2021 | Series A |
Round details for Fifty Years
Amounts, full round histories and every co-investor in Fifty Years' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
77 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| The company develops a platform and products for advanced therapeutics, including gene therapies, cell therapies, and biologics. | Healthcare & Biotech | Portfolio page | ||
| Aalo Atomics builds mass-manufactured nuclear power plants designed to power data centers and other applications | EducationIndustrial & Manufacturing | Portfolio page | ||
| Adaption Labs provides a full stack platform for custom model training, data optimization, and continuous learning at inference. | AI & Machine LearningEnterprise Software | Feb 2026Seed | Page + round | |
| Ansa Biotechnologies synthesizes custom DNA sequences for its customers. | Healthcare & Biotech | Portfolio page | ||
| Antora develops and deploys thermal battery storage systems for industrial heat and power | Industrial & ManufacturingEducation | Portfolio page | ||
| Apollo Research conducts fundamental research into the science of scheming in AI systems and develops ways to detect and mitigate it. | AI & Machine LearningCybersecurity | Portfolio page | ||
| Aralez Bio produces noncanonical amino acids used in medicine | Healthcare & Biotech | Portfolio page | ||
| Astranis designs, manufactures, tests, and operates geostationary orbit satellites for commercial and government customers. | Space & DefenseAI & Machine Learning | Portfolio page | ||
| Atom Computing builds highly scalable, gate-based quantum computers with arrays of optically-trapped neutral atoms | Healthcare & BiotechIndustrial & Manufacturing | Portfolio page | ||
| Avro Life Science is a clinical stage biotech company that develops topical platform technology for delivering drugs into the skin | Healthcare & Biotech | Portfolio page | ||
| BioRender provides scientific figure and illustration software | Healthcare & Biotech | Portfolio page | ||
| BIOS Health develops neural interfaces and AI to read and write the body's neural data to understand and correct faulty signals in real-time | Healthcare & Biotech | Portfolio page | ||
| Bloom provides a texting platform for healthcare communication | Healthcare & Biotech | Portfolio page | ||
| The company is building a helpful robot for every home | Robotics & Hardware | Mar 2025Seed | Page + round | |
| The company designs custom, architect-grade spaces and builds them in weeks, not years. | Real Estate & Construction | Portfolio page | ||
| Clippership develops autonomous wind-powered vessels for AI compute on the open ocean | AI & Machine LearningSpace & Defense | Portfolio page | ||
| Cofactor Genomics develops diagnostic tools using RNA to predict patient response to immunotherapy | Healthcare & Biotech | Portfolio page | ||
| Cosmic designs and manufactures a premium four-seat electric aircraft for personal flight. | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| Deepcell develops an AI-integrated platform for imaging, analysis, and enrichment of viable cells. | Healthcare & Biotech | Dec 2017Seed | Page + round | |
| Digital Biology accelerates protein engineering by providing scalable and relevant data for protein design and development. | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- fiftyyears.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 1 Dec 2017
- Companies checked
- 77
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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