Investors / United States / Lionheart Ventures
Lionheart Ventures
Venture capital · San Francisco, CA, United States · North America
Lionheart Ventures is a venture capital firm that invests in transformative technologies, with a focus on artificial intelligence and frontier mental health technologies. It backs founders developing technologies it believes can impact humanity at meaningful scale while generating returns for investors.
Invests inHealthcare & BiotechAI & Machine Learning
In its own wordsartificial intelligencemental healthpsychedelic medicineneuromodulationdata sovereigntyhealthcare
Your fit with Lionheart Ventures
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsLionheart Ventures lists 9 checked portfolio companies on its own site and is named in 1 funding round. Its most frequent entry is Seed, 100% of the companies with a known first round. Its largest themes are Healthcare & Biotech (33%), AI & Machine Learning (17%) and Enterprise Software (8%). 50% of its companies are based in United States. It invests most often alongside DecentraNet, General Catalyst and Insight Partners.
Counts come from funding rounds that name Lionheart Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Entry stage
share of companies by the stage of its first roundLionheart Ventures does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 100% |
| Series A | 0% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 1 | 0 |
| '25 | 0 | 0 |
| '26 | 0 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 19th | 9 companies |
| Recent activity | 46th | 0 rounds in 12 months |
| Early stage | 100th | 100% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 62th | 33% in its largest sector |
| Reach | 58th | 3 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 33% | 15% |
| AI & Machine Learning | 17% | 18% |
| Enterprise Software | 8% | 8% |
| Consumer | 8% | 3% |
| Industrial & Manufacturing | 8% | 7% |
| Climate & Energy | 8% | 1% |
| Education | 8% | 7% |
| Media & Entertainment | 8% | 4% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| DecentraNet | 2 |
| General Catalyst | 2 |
| Insight Partners | 2 |
| Lightspeed Venture Partners | 2 |
| Lowercarbon Capital | 2 |
| Ossian Capital | 2 |
| Singularity Capital | 2 |
| Y Combinator | 2 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers889%
- No longer answers00%
- Points to another company111%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherCompare Lionheart Ventures head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Lionheart Ventures| Date | Company | Stage |
|---|---|---|
| 1 Aug 2024 | Seed |
Round details for Lionheart Ventures
Amounts, full round histories and every co-investor in Lionheart Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
9 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| 2A Biosciences is developing precision agonists to restore neural circuitry and immune balance | Healthcare & Biotech | Portfolio page | ||
| Anthropic develops AI models and products, including the Claude models, and conducts AI safety research. | AI & Machine LearningEnterprise Software | Portfolio page | ||
| Portfolio page | ||||
| The company specializes in full-depth reclamation, crushing and reusing on-site materials to rebuild roads with minimal waste. | ConsumerIndustrial & Manufacturing | Portfolio page | ||
| Charm Industrial removes CO₂ from the atmosphere by capturing it with plants, converting biomass into a stable liquid, and pumping it underground for permanent storage. | Climate & Energy | Portfolio page | ||
| Clerkenwell Health conducts clinical trials for mental health and neurological conditions | Healthcare & Biotech | Portfolio page | ||
EducationMedia & Entertainment | Portfolio page | |||
| Entheos Labs harnesses the unique potential of psychoactive plants to power breakthrough treatments for mental health disorders | Healthcare & Biotech | Portfolio page | ||
| Piramidal develops brain foundation models using EEG data for various applications, including seizure detection and real-time EEG monitoring | Healthcare & BiotechAI & Machine Learning | Aug 2024Seed | Funding round |
About this data
site last read 5 Nov 2026- Site
- lionheart.vc
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 1 Aug 2024
- Companies checked
- 9
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
Get Lionheart Ventures' profile as data
Pull Lionheart Ventures' portfolio, co-investors and changes through one API key or MCP, open every portfolio row, compare it with other firms, and get an email when it adds a company or files a fund.
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