Investors / United States / Longwood Fund
Longwood Fund
Venture capital · Boston, MA, United States · North America
Longwood Fund is a life science venture investor that both creates new biotechnology companies and invests in private, early-stage biotech companies. It works with academic and industry networks to found companies and to support portfolio companies developing therapeutics toward clinical proof of concept.
Invests inHealthcare & Biotech
In its own wordsbiotechlife sciencestherapeuticscompany creationhealthcare
Your fit with Longwood Fund
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See how your round matches what it backs, point by point.
Or find every investor that fitsLongwood Fund lists 11 checked portfolio companies on its own site and is named in 9 funding rounds. Its most frequent entry is Series B, 75% of the companies with a known first round. Its largest theme is Healthcare & Biotech (100%). 70% of its companies are based in United States. It invests most often alongside SR One, Atlas Venture and Forbion.
Counts come from funding rounds that name Longwood Fund, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 25% |
| Series B | 75% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 3 | 0 |
| '26 | 6 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 27th | 11 companies |
| Recent activity | 89th | 6 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 96th | 27% of companies confirmed by a round |
| Sector focus | 100th | 100% in its largest sector |
| Reach | 70th | 4 countries |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| SR One | 3 |
| Atlas Venture | 2 |
| Forbion | 2 |
| Foresite Capital | 2 |
| Lilly Asia Ventures | 2 |
| Regeneron Ventures | 2 |
| Sofinnova | 2 |
| AN Venture Partners | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers11100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 100% | 15% |
Co-investor network
who it backs companies with, and who they back togetherCompare Longwood Fund head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Funds
from public registers and its siteRecent portfolio activity
when companies last raised with Longwood Fund| Date | Company | Stage |
|---|---|---|
| 13 Aug 2026 | Series B | |
| 22 Jul 2026 | Series B | |
| 28 Apr 2026 | Series A | |
| 13 Apr 2026 | Series B | |
| 7 Jan 2026 | Series B | |
| 3 Nov 2025 | Series B | |
| 30 Sept 2025 | Series A | |
| 22 Sept 2025 | Series B |
Round details for Longwood Fund
Amounts, full round histories and every co-investor in Longwood Fund's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
11 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Nov 2025Series B | Page + round | |||
| Avenzo Therapeutics develops next-generation oncology therapies to transform cancer treatment | Healthcare & Biotech | Sept 2025Series B | Page + round | |
| The company aims to inhibit the active ON state of RAS signaling in cancer, using expert understanding of RAS signaling biology to inform rational drug design. | Healthcare & Biotech | Portfolio page | ||
| Bicycle Therapeutics is developing precision-guided therapeutics to target solid tumor cancers and other therapeutic applications | Healthcare & Biotech | Portfolio page | ||
| Portfolio page | ||||
| Colorescience develops and sells mineral sunscreen and clinical skincare products. | Healthcare & Biotech | Portfolio page | ||
| Apr 2026Series A | Page + round | |||
| Crystalys Therapeutics develops new therapeutics to address unmet medical needs, specifically for people living with gout. | Healthcare & Biotech | Sept 2025Series A · 2 rounds | Funding round | |
| Khartis Therapeutics develops oral therapies for patients with immune-mediated and chronic diseases | Healthcare & Biotech | Aug 2026Series B | Funding round | |
| Mediar Therapeutics is developing treatments for fibrotic diseases by targeting the myofibroblast cell | Healthcare & Biotech | Jan 2026Series B | Funding round | |
| Neomorph develops molecular glue degraders to target and destroy disease-causing proteins. | Healthcare & Biotech | Apr 2026Series B | Funding round |
About this data
site last read 5 Nov 2026- Site
- longwoodfund.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 22 Sept 2025
- Companies checked
- 11
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
Get Longwood Fund's profile as data
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