Investors / United States / Madrona
Madrona
Venture capital · Seattle, WA, United States · North America
Madrona is a venture capital firm founded in Seattle in 1995 that invests in founding teams from incubation and seed through early growth and acceleration stages. It works alongside founders with capital, strategy, and operational support, and opened a Silicon Valley office in Palo Alto in 2022.
Invests inAI & Machine LearningEnterprise Software
In its own wordsaienterprise softwareconsumerbiotechdeveloper toolssecurity
Your fit with Madrona
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsMadrona lists 160 checked portfolio companies on its own site and is named in 37 funding rounds, 15 of them as lead. Its most frequent entry is Seed, 31% of the companies with a known first round. Its largest themes are AI & Machine Learning (30%), Enterprise Software (16%) and Healthcare & Biotech (10%). 91% of its companies are based in United States. It invests most often alongside Insight Partners, Accel and Salesforce Ventures.
Counts come from funding rounds that name Madrona, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Madrona's whole history. Rounds on record name 33 companies; its own site lists 160. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 31% |
| Series A | 31% |
| Series B | 22% |
| Growth | 16% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 1 | 0 |
| '23 | 0 | 0 |
| '24 | 1 | 0 |
| '25 | 15 | 5 |
| '26 | 20 | 10 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 98th | 162 companies |
| Recent activity | 99th | 23 rounds in 12 months |
| Early stage | 61th | 31% of entries at pre-seed or seed |
| Evidence | 86th | 15% of companies confirmed by a round |
| Sector focus | 53th | 30% in its largest sector |
| Reach | 84th | 6 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| AI & Machine Learning | 30% | 18% |
| Enterprise Software | 16% | 8% |
| Healthcare & Biotech | 10% | 15% |
| Fintech | 8% | 12% |
| Cybersecurity | 7% | 4% |
| Education | 4% | 7% |
| Media & Entertainment | 4% | 4% |
| E-commerce & Marketplaces | 4% | 6% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Insight Partners | 14 |
| Accel | 8 |
| Salesforce Ventures | 8 |
| Sequoia Capital | 8 |
| Andreessen Horowitz | 7 |
| Ascend | 6 |
| Greylock | 6 |
| General Catalyst | 5 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers15194%
- No longer answers00%
- Points to another company96%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with Insight Partners
Compare Madrona head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Madrona| Date | Company | Stage |
|---|---|---|
| 10 Nov 2026 | Series B | |
| 4 Nov 2026 | Series A | |
| 1 Sept 2026 | Seed Led | |
| 5 Aug 2026 | Series C+ Led | |
| 29 Jul 2026 | Seed Led | |
| 18 Jun 2026 | Series C+ | |
| 9 Jun 2026 | Seed | |
| 28 May 2026 | Series A Led |
Round details for Madrona
Amounts, full round histories and every co-investor in Madrona's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
160 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| A-Alpha Bio harnesses synthetic biology and machine learning to precisely engineer high-impact medicines | Healthcare & Biotech | Portfolio page | ||
| Accolade provides personalized support, on-demand care, and benefits and health guidance to its members. | Healthcare & Biotech | Portfolio page | ||
AI & Machine LearningFintech | Oct 2025Series C+ | Funding round | ||
| Aizen Therapeutics is developing a portfolio of oral peptide therapeutics to transform the lives of patients and families burdened by chronic immune disorders. | Healthcare & Biotech | Portfolio page | ||
AI & Machine LearningEnterprise Software | Nov 2025Series A | Funding round | ||
| The company develops and deploys clinical AI agents for healthcare | Healthcare & Biotech | Mar 2026Series A | Funding round | |
| Amperity provides a customer data platform that powers real-time customer experience for enterprise brands | AI & Machine LearningEnterprise Software | Portfolio page | ||
| Anagram Security provides security awareness and developer training | EducationCybersecurity | Portfolio page | ||
| Portfolio page | ||||
| Anthropic develops AI models and products, including the Claude models, and conducts AI safety research. | AI & Machine LearningEnterprise Software | Portfolio page | ||
| Anzen provides an AI-native end-to-end system for the policy lifecycle in the insurance industry | FintechAI & Machine Learning | Nov 2025Series A | Funding round | |
| Archon Bio is a biotechnology company developing geometrically tunable protein therapeutics | Healthcare & Biotech | Portfolio page | ||
| WisdomAI builds and validates the business context behind accurate answers and applies it in production across various analytics platforms. | AI & Machine LearningEnterprise Software | Portfolio page | ||
| The company provides supply chain planning software | Industrial & Manufacturing | Portfolio page | ||
| Axiom does mathematical research and publishes papers and formalizations. | EducationRobotics & Hardware | Oct 2025Seed · 2 rounds | Page + round | |
| Battlesnake is a competitive game where users write code to control a snake and compete against others. | GamingEducation | Portfolio page | ||
| Bobsled provides an operating system for data products | AI & Machine LearningFintech | Portfolio page | ||
| Bocada provides backup and storage monitoring software for enterprises and managed service providers. | Enterprise SoftwareCybersecurity | Portfolio page | ||
| Booster delivers gasoline, diesel, and other fuels directly to vehicles, fleets, and equipment | E-commerce & MarketplacesMobility & Logistics | Portfolio page | ||
| Branch provides a mobile measurement and deep linking platform for businesses | Media & EntertainmentE-commerce & Marketplaces | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- madrona.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 15 Nov 2022
- Companies checked
- 160
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
Get Madrona's profile as data
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