Investors / ONCE Ventures
ONCE Ventures
Corporate VC
ONCE Ventures is the venture arm of Otsuka focused on companies that deliver meaningful improvements to consumer health. It invests up to $5 million in Series A and B companies in its focus areas, and may consider earlier and later stages case by case.
Invests inHealthcare & Biotech
In its own wordsconsumer healthsupplementsdigital healthmicrobiomepersonalized nutritionwomen's health
Your fit with ONCE Ventures
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsONCE Ventures lists 7 checked portfolio companies on its own site. Its largest themes are Healthcare & Biotech (71%), AI & Machine Learning (14%) and Food & Agriculture (14%). 100% of its companies are based in United States. It invests most often alongside 500 Emerging Europe, APY Ventures and Astir Ventures.
No funding round on record names ONCE Ventures yet, so the figures come from its portfolio page.
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 12th | 7 companies |
| Recent activity | 46th | 0 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 92th | 71% in its largest sector |
| Reach | 19th | 1 country |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers7100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 71% | 15% |
| AI & Machine Learning | 14% | 18% |
| Food & Agriculture | 14% | 3% |
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with 500 Emerging Europe
Compare ONCE Ventures head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Portfolio
7 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Curio Digital Therapeutics provides digital-first behavioral health solutions for women's mental health | Healthcare & Biotech | Portfolio page | ||
| Kanza AI develops a Clinical Reasoning System for physicians | Healthcare & BiotechAI & Machine Learning | Portfolio page | ||
| New Culture makes animal-free dairy products, including cheese, using traditional cheese-making and innovative food science. | Food & Agriculture | Portfolio page | ||
| Prenexus Health focuses on promoting health and wellness through the research, development and production of branded prebiotic ingredients for dietary supplement, food and beverage products. | Healthcare & Biotech | Portfolio page | ||
| Solaria Bio develops and sells a plant-sourced synbiotic product called Bōndia to protect against bone loss | Healthcare & Biotech | Portfolio page | ||
| Vivoo sells at-home health and wellness tests | Healthcare & Biotech | Portfolio page | ||
| Portfolio page |
About this data
site last read 5 Nov 2026- Site
- onceventures.com
- Last read
- 5 Nov 2026
- Watching since
- 6 Nov 2026
- Companies checked
- 7
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
Get ONCE Ventures' profile as data
Pull ONCE Ventures' portfolio, co-investors and changes through one API key or MCP, open every portfolio row, compare it with other firms, and get an email when it adds a company or files a fund.
Work email, sign-in link by email. Already have an account? Log in- Ask AI5 plain-English investor searches a day
- Full listsEvery portfolio row and two-firm overlap
- API and MCP100 REST or MCP calls a month, one key
- AlertsFollow 5 investors for portfolio and fund changes
$ curl -H "X-API-Key: YOUR_KEY" \
https://api.vcinfo.io/v1/firms/onceventures.com
# also
GET /v1/firms/onceventures.com/portfolio
GET /v1/firms/onceventures.com/coinvestors
GET /v1/firms/onceventures.com/news