Investors / United States / OpenAI Startup Fund
OpenAI Startup Fund
Venture capital · San Francisco, CA, United States · North America
The OpenAI Startup Fund is a $175 million fund that partners with early-stage startups applying artificial intelligence. It is managed by a dedicated team with expertise in investing, ML, engineering, talent and operations, and its investors include Microsoft and other OpenAI partners, though OpenAI itself is not an investor.
Invests inAI & Machine LearningHealthcare & Biotech
In its own wordsartificial intelligencehealthcarelegaleducationenergyscience
Your fit with OpenAI Startup Fund
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsOpenAI Startup Fund lists 19 checked portfolio companies on its own site and is named in 26 funding rounds, 10 of them as lead. Its most frequent entry is Series A, 47% of the companies with a known first round. Its largest themes are AI & Machine Learning (33%), Healthcare & Biotech (15%) and Cybersecurity (9%). 85% of its companies are based in United States. It invests most often alongside Founders Fund, Kleiner Perkins and Andreessen Horowitz.
Counts come from funding rounds that name OpenAI Startup Fund, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 26% |
| Series A | 47% |
| Series B | 11% |
| Growth | 16% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 2 | 0 |
| '25 | 14 | 5 |
| '26 | 10 | 5 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 51th | 20 companies |
| Recent activity | 97th | 13 rounds in 12 months |
| Early stage | 60th | 26% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 62th | 33% in its largest sector |
| Reach | 58th | 3 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| AI & Machine Learning | 33% | 18% |
| Healthcare & Biotech | 15% | 15% |
| Cybersecurity | 9% | 4% |
| Enterprise Software | 9% | 8% |
| Space & Defense | 9% | 3% |
| Fintech | 6% | 12% |
| Education | 6% | 7% |
| Industrial & Manufacturing | 3% | 7% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Founders Fund | 4 |
| Kleiner Perkins | 4 |
| Andreessen Horowitz | 3 |
| Bain Capital Ventures | 3 |
| DST Global | 3 |
| Lux Capital | 3 |
| SV Angel | 3 |
| Sequoia Capital | 3 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers1895%
- No longer answers00%
- Points to another company15%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherCompare OpenAI Startup Fund head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with OpenAI Startup Fund| Date | Company | Stage |
|---|---|---|
| 21 Oct 2026 | Series A Led | |
| 28 Sept 2026 | Series C+ Led | |
| 14 Jul 2026 | Series C+ | |
| 11 Jun 2026 | Series A | |
| 23 Apr 2026 | Series B Led | |
| 30 Mar 2026 | Series A | |
| 25 Mar 2026 | Series A Led | |
| 20 Mar 2026 | Series A |
Round details for OpenAI Startup Fund
Amounts, full round histories and every co-investor in OpenAI Startup Fund's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
19 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| The company provides cybersecurity solutions to protect against AI-powered attacks and deepfakes. | Cybersecurity | Sept 2025Series A · 2 rounds | Funding round | |
| Ambience Healthcare provides AI solutions for healthcare systems to improve clinical, quality, and financial outcomes. | Healthcare & Biotech | Jul 2025Series C+ | Funding round | |
| The company develops and provides AI agents for physical operations and supply chain management | AI & Machine LearningIndustrial & Manufacturing | Mar 2026Seed | Funding round | |
| biossil advances late-stage programs for life-threatening diseases | Healthcare & Biotech | Apr 2026Series B · 2 rounds | Funding round | |
| Chai Discovery builds the computer-aided design suite for molecules | Healthcare & Biotech | Aug 2025Series A · 3 rounds | Funding round | |
| The company designs therapeutic neurotechnology to manage cancer from inside the body | Healthcare & Biotech | Oct 2026Series A | Funding round | |
| Corridor secures AI coding agents as they write code, enforces what's safe to ship, and scales with teams as agents take on more. | CybersecurityAI & Machine Learning | Mar 2026Series A | Funding round | |
| The company provides AI agents for automating office work tasks | AI & Machine LearningEnterprise Software | Aug 2025Seed | Funding round | |
| Evertune provides a platform for managing the AI customer journey, including tracking organic visibility, optimizing content, and advertising inside and outside AI conversations. | AI & Machine LearningMedia & Entertainment | Aug 2025Series A | Funding round | |
| Gigi provides a network for agents to find and connect with people through trusted relationships | AI & Machine LearningEnterprise Software | Sept 2025Seed · 2 rounds | Funding round | |
| Harvey develops AI software for legal and professional services | Legal & ComplianceAI & Machine Learning | Jun 2025Series C+ | Funding round | |
| Isara reads customer conversations to identify those at risk of leaving and alerts the relevant teams | Space & DefenseSpace & Defense | Mar 2026Series A | Funding round | |
| Mar 2026Series A | Funding round | |||
| Merge Labs operates to redefine Web 2 ecosystems and products into sustainable Web 3 variants | FintechCybersecurity | Jan 2026Seed | Funding round | |
| Poetic develops an AI system that learns and automates business processes | AI & Machine LearningFintech | Jun 2026Series A | Funding round | |
| The company develops and provides a language learning application that uses AI to help users learn languages through real conversations. | EducationEducation | Dec 2024Series C+ | Funding round | |
| Unify provides an AI-native platform for sales teams to automate outbound sales processes | AI & Machine LearningSpace & Defense | Jul 2025Series B | Funding round | |
| Valthos develops AI systems to identify biological threats and design medical countermeasures in real time. | Healthcare & BiotechAI & Machine Learning | Oct 2025Seed | Funding round | |
AI & Machine LearningEnterprise Software | May 2025Round | Funding round |
About this data
site last read 5 Nov 2026- Site
- openai.fund
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 4 Nov 2024
- Companies checked
- 19
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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