Investors / United States / Plaisance Capital Management
Plaisance Capital Management
Venture capital · Cambridge, MA, United States · North America
Plaisance Capital Management is an investment management company established in 2020 that invests in and incubates biotech startups. It provides capital, mentorship and guidance to founders working on healthcare challenges.
Invests inHealthcare & Biotech
In its own wordsbiotechhealthcarelife sciencesincubation
Your fit with Plaisance Capital Management
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsPlaisance Capital Management lists 9 checked portfolio companies on its own site and is named in 2 funding rounds. Its most frequent entry is Series B, 50% of the companies with a known first round. Its largest theme is Healthcare & Biotech (100%). 75% of its companies are based in United States. It invests most often alongside 3E Bioventures Capital, StartX and Vivo Capital.
Counts come from funding rounds that name Plaisance Capital Management, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Entry stage
share of companies by the stage of its first roundPlaisance Capital Management does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 0% |
| Series B | 50% |
| Growth | 50% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 1 | 0 |
| '26 | 1 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 19th | 9 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 100th | 100% in its largest sector |
| Reach | 58th | 3 countries |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| 3E Bioventures Capital | 3 |
| StartX | 2 |
| Vivo Capital | 2 |
| Ambit Health Ventures | 1 |
| Atinum Investment | 1 |
| Bessemer Venture Partners | 1 |
| BioTrack Capital | 1 |
| Boutique Venture Partners | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers9100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 100% | 15% |
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with 3E Bioventures Capital
Compare Plaisance Capital Management head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Plaisance Capital Management| Date | Company | Stage |
|---|---|---|
| 18 May 2026 | Series C+ | |
| 10 Dec 2025 | Series B |
Round details for Plaisance Capital Management
Amounts, full round histories and every co-investor in Plaisance Capital Management's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
9 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| BlossomHill Therapeutics designs and develops innovative small molecules to overcome the limitations of existing cancer therapies. | Healthcare & Biotech | Dec 2025Series B | Funding round | |
| Cephla builds custom platforms that help labs automate, scale, and run connected workflows with smart hardware and open-source tools | Healthcare & Biotech | Portfolio page | ||
| Cytek Biosciences develops and sells flow cytometry systems and related products and services. | Healthcare & Biotech | Portfolio page | ||
| Ellis Bio develops and sells epigenomic tools and technologies, including kits for DNA methylation analysis | Healthcare & Biotech | Portfolio page | ||
| Full-Life Technologies Limited is a global radiotherapeutics company that develops and produces radiopharmaceuticals for patients worldwide. | Healthcare & Biotech | May 2026Series C+ | Funding round | |
| Hebecellcorp develops and commercializes cell-based therapeutics to treat incurable diseases | Healthcare & Biotech | Portfolio page | ||
| SEDEC THERAPEUTICS develops therapeutics for autoimmune diseases | Healthcare & Biotech | Portfolio page | ||
| Smartlens Health develops and offers smart contact lenses and related technologies for continuous monitoring, diagnosis, and treatment optimization of ophthalmic diseases | Healthcare & Biotech | Portfolio page | ||
| Subtle Medical develops vendor-neutral software solutions that improve image quality on regular and accelerated image protocols, allowing radiologists to expedite patient care. | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- plaisancecap.com
- Last read
- 5 Nov 2026
- Watching since
- 6 Nov 2026
- Rounds since
- 10 Dec 2025
- Companies checked
- 9
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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