Investors / United States / Portal Innovations
Portal Innovations
Venture capital · Chicago, United States · North America
Portal Innovations is a venture development platform that provides seed capital, fully equipped lab and office space, and operational support to science-driven startups. It also uses university relationships to source technologies and an in-house scientific team to support portfolio companies on strategy, data, and commercialization.
Invests inHealthcare & Biotech
In its own wordslife sciencesbiotechmedtechlab spaceventure developmentemerging ecosystems
Your fit with Portal Innovations
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsPortal Innovations lists 24 checked portfolio companies on its own site and is named in 1 funding round. Its most frequent entry is Series A, 100% of the companies with a known first round. Its largest theme is Healthcare & Biotech (100%). 100% of its companies are based in United States. It invests most often alongside Viva BioInnovator, DCVC and Draper Associates.
Counts come from funding rounds that name Portal Innovations, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Portal Innovations' whole history. Rounds on record name 1 company; its own site lists 24. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 100% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 0 | 0 |
| '26 | 1 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 59th | 24 companies |
| Recent activity | 59th | 1 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 61th | 4% of companies confirmed by a round |
| Sector focus | 100th | 100% in its largest sector |
| Reach | 19th | 1 country |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Viva BioInnovator | 3 |
| DCVC | 2 |
| Draper Associates | 2 |
| Green Park & Golf Ventures | 2 |
| Mission BioCapital | 2 |
| Allegis Capital | 1 |
| AllerFund | 1 |
| Astellas Venture Management | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers24100%
- No longer answers00%
- Points to another company00%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 100% | 15% |
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with Viva BioInnovator
Compare Portal Innovations head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Portal Innovations| Date | Company | Stage |
|---|---|---|
| 20 Jun 2026 | Series A |
Round details for Portal Innovations
Amounts, full round histories and every co-investor in Portal Innovations' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
24 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Alnair Therapeutics is developing a nanoparticle platform for conditional activation of small molecules across all solid tumors. | Healthcare & Biotech | Portfolio page | ||
| ARase Therapeutics develops first-in-class therapeutics targeting ADP-ribose Hydrolases for cancer treatment | Healthcare & Biotech | Portfolio page | ||
| Cardiosense develops a heart failure monitoring solution to noninvasively determine Pulmonary Capillary Wedge Pressure at the point of care. | Healthcare & Biotech | Portfolio page | ||
| CiRC Biosciences is a regenerative medicine company focused on degenerative diseases that destroy functional cells, causing the gradual loss of physical abilities. | Healthcare & Biotech | Portfolio page | ||
| ClostraBio develops probiotics and metabolite delivery solutions for gut health and diseases | Healthcare & Biotech | Portfolio page | ||
| The company is developing a cell therapy to treat solid tumors using a rare and potent circulating T cell population found in the blood | Healthcare & Biotech | Portfolio page | ||
| Dimension Bio is a biotechnology company pioneering regenerative therapeutics | Healthcare & Biotech | Portfolio page | ||
| Grove Biopharma is pioneering Bionic Biologics, a breakthrough synthetic modality for developing novel therapeutics that target intracellular protein-protein interactions. | Healthcare & Biotech | Portfolio page | ||
| Inomagen Therapeutics is developing a non-viral disease-modifying gene therapy to improve the treatment of atrial fibrillation. | Healthcare & Biotech | Portfolio page | ||
| Iterion Therapeutics is a clinical-stage, biopharmaceutical company developing novel therapeutics for cancer. | Healthcare & Biotech | Portfolio page | ||
| March.biosciences is a clinical-stage company developing CAR-T cell strategies to address hematological cancers. | Healthcare & Biotech | Portfolio page | ||
| Moonlight Therapeutics is developing a new skin based therapy to transform the lives of people living with food allergies | Healthcare & Biotech | Portfolio page | ||
| Novabloc is an investigational medical device being studied for targeted, long-lasting postoperative pain relief through a novel electrical stimulation paradigm. | Healthcare & Biotech | Portfolio page | ||
| Novascan develops and manufactures cancer detection technology, including a device called MarginScan that detects and localizes cancer at the margins of surgical excisions | Healthcare & Biotech | Portfolio page | ||
| Pelagos Pharmaceuticals is developing a new class of therapeutics called exercise mimetics | Healthcare & Biotech | Portfolio page | ||
| ReAx Biotechnologies is a company that delivers therapies for challenging protein targets using its discovery platform. | Healthcare & Biotech | Portfolio page | ||
| Rhaeos assesses hydrocephalus shunt flow with a non-invasive device called FlowSense | Healthcare & Biotech | Portfolio page | ||
| RNAV8 Bio engineers mRNA to treat disease | Healthcare & Biotech | Portfolio page | ||
| Syntax Bio programs stem cells toward various cell types, including pancreatic beta cells, using its proprietary Cellgorithm technology. | Healthcare & Biotech | Jun 2026Series A | Page + round | |
| Syntis Bio is developing oral therapies that harness the small intestine's biology to address various healthcare challenges | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- portalinnovations.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 20 Jun 2026
- Companies checked
- 24
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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