Investors / What If Ventures
What If Ventures
Venture capital
What If Ventures is an investment firm that backs companies across sectors including nuclear energy, neuroscience, psychedelic medicine, AI, quantum computing, space technology and fintech. It also runs an 8-week accelerator fellowship for digital and mental health companies and invites founders to apply for funding.
Invests inHealthcare & BiotechAI & Machine Learning
In its own wordsmental healthdigital healthaispacequantum computingpsychedelics
Your fit with What If Ventures
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsWhat If Ventures lists 16 checked portfolio companies on its own site and is named in 4 funding rounds. Its most frequent entry is Series A, 33% of the companies with a known first round. Its largest themes are Healthcare & Biotech (48%), AI & Machine Learning (33%) and Education (10%). 100% of its companies are based in United States. It invests most often alongside Calm Ventures, Capital Factory and Gaingels.
Counts come from funding rounds that name What If Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not What If Ventures' whole history. Rounds on record name 4 companies; its own site lists 16. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundWhat If Ventures does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 33% |
| Series B | 33% |
| Growth | 33% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 2 | 0 |
| '26 | 2 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 42th | 16 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 52th | 0% of companies confirmed by a round |
| Sector focus | 82th | 48% in its largest sector |
| Reach | 19th | 1 country |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Calm Ventures | 4 |
| Capital Factory | 3 |
| Gaingels | 3 |
| Palo Santo | 3 |
| Able Partners | 2 |
| Alumni Ventures | 2 |
| Crosscourt Ventures | 2 |
| Grant Park Ventures | 2 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers1594%
- No longer answers00%
- Points to another company16%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 48% | 15% |
| AI & Machine Learning | 33% | 18% |
| Education | 10% | 7% |
| Industrial & Manufacturing | 10% | 7% |
Co-investor network
who it backs companies with, and who they back togetherCompare What If Ventures head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with What If Ventures| Date | Company | Stage |
|---|---|---|
| 27 May 2026 | Series B | |
| 21 Apr 2026 | Series C+ | |
| 13 May 2025 | Round | |
| 14 Jan 2025 | Series A |
Round details for What If Ventures
Amounts, full round histories and every co-investor in What If Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
16 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| 2A Biosciences is developing precision agonists to restore neural circuitry and immune balance | Healthcare & Biotech | Portfolio page | ||
| Aalo Atomics builds mass-manufactured nuclear power plants designed to power data centers and other applications | EducationIndustrial & Manufacturing | Portfolio page | ||
| Aeon develops advanced tactical weapon systems | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| Affect Therapeutics provides mental health and addiction treatment services. | Healthcare & Biotech | Portfolio page | ||
| The company develops and manufactures autonomous robotics systems for defense applications | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| The company operates a pharmacy that delivers prescriptions and offers 24/7 support | Healthcare & Biotech | Portfolio page | ||
| Alto Neuroscience develops biology-driven medicines for neuropsychiatric conditions | Healthcare & Biotech | Portfolio page | ||
| AmyriAD is developing a novel therapy to improve cognition and independent global function in patients with Alzheimer’s disease | Healthcare & Biotech | Portfolio page | ||
| Applied Cognition develops treatments and measurements for the glymphatic system to prevent and treat diseases such as Alzheimer's and Parkinson's. | Healthcare & Biotech | Portfolio page | ||
| AptiHealth provides integrated behavioral healthcare services to individuals, including therapy, medication management, and care coordination. | Healthcare & Biotech | Portfolio page | ||
| AtaiBeckley develops mental health treatments | Healthcare & Biotech | Portfolio page | ||
Healthcare & Biotech | Portfolio page | |||
| Apr 2026Series C+ | Funding round | |||
| Saildrone delivers autonomous maritime defense and ocean intelligence services | AI & Machine LearningAI & Machine Learning | May 2025Round | Funding round | |
| The company provides an AI-powered mental health support tool that offers 24/7 emotional support and helps users connect thoughts, feelings, and behaviors. | Healthcare & BiotechAI & Machine Learning | Jan 2025Series A | Funding round | |
| Thea Energy develops fusion power systems using stellarator technology to create a limitless source of zero-emission energy. | EducationIndustrial & Manufacturing | May 2026Series B | Funding round |
About this data
site last read 5 Nov 2026- Site
- whatif.vc
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 14 Jan 2025
- Companies checked
- 16
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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