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Investors / 5AM Ventures / Compare with Protagonist

5AM Ventures vs Protagonist

5AM Ventures lists 50 portfolio companies and has joined 10 funding rounds; Protagonist lists 15 companies and has joined 7 rounds. 5AM Ventures comes in most often at Series B (44% of its entries), Protagonist comes in most often at Seed (43% of its entries). 1 company is on both portfolios, among them Epirus.

50Portfolio companies15
10Funding rounds joined7
3Rounds led1
5Rounds, last 12 months2
$20M to $100MTypical round it comes in at$20M to $100M
0%Sites no longer answering0%
Show as a table
5AM Ventures and Protagonist, head to head
5AM VenturesProtagonist
Portfolio companies5015
Funding rounds joined107
Rounds led31
Rounds, last 12 months52
Typical round it comes in at$20M to $100M$20M to $100M
Sites no longer answering0%0%

Where they come in

share of entries by stage
Pre-seed0%0%
Seed11%43%
Series A22%43%
Series B44%0%
Growth22%14%

5AM VenturesProtagonist

Show as a table
Entry stages of 5AM Ventures and Protagonist, share of entries
5AM VenturesProtagonist
Pre-seed0%0%
Seed11%43%
Series A22%43%
Series B44%0%
Growth22%14%

Themes

share of checked companies
Healthcare & Biotech77%4%
AI & Machine Learning11%24%
Fintech4%20%
Cybersecurity2%12%
Robotics & Hardware2%8%
Industrial & Manufacturing0%8%

5AM VenturesProtagonist

Show as a table
Themes of 5AM Ventures and Protagonist, share of checked companies
5AM VenturesProtagonist
Healthcare & Biotech77%4%
AI & Machine Learning11%24%
Fintech4%20%
Cybersecurity2%12%
Robotics & Hardware2%8%
Industrial & Manufacturing0%8%

Companies both back

1

Shared companies are those both firms' own portfolio pages list, each checked against the company's site. The same comparison through the API is POST /v1/overlap, for up to 20 firms. How the data is graded

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Compare 5AM Ventures and Protagonist as data

Pull both portfolios and every co-investor through one API key or MCP, and lay up to 20 firms side by side with POST /v1/overlap. A free account adds Ask AI searches and alerts when either firm adds a company.

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  • Ask AI5 plain-English investor searches a day
  • Full listsEvery portfolio row and two-firm overlap
  • API and MCP100 REST or MCP calls a month, one key
  • AlertsFollow 5 investors for portfolio and fund changes
VCinfo API
$ curl -H "X-API-Key: YOUR_KEY" \
  https://api.vcinfo.io/v1/firms/5amventures.com/portfolio

# also
GET /v1/firms/protagonist.co/portfolio
GET /v1/firms/5amventures.com/coinvestors
The same data as an MCP server for Claude, Cursor and other AI tools. Set up MCP · Docs · Pricing