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Investors / United States / 2048 Ventures

2048 Ventures

Venture capital · Princeton, NJ, United States · North America

2048.vc

2048 Ventures is a venture capital firm that makes first-check investments in pre-seed and seed rounds, typically writing checks of $500K to $3M. It has deep roots in NYC and Boston and invests in companies across the US.

Invests inHealthcare & BiotechAI & Machine Learning

In its own wordsaideep techhealthbiodata moatssystems of record

Your fit with 2048 Ventures

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76portfolio companies
12funding rounds on record5 led
10rounds, last 12 months
$5M to $20Mtypical round it comes in at
Seedmost frequent entry

2048 Ventures lists 76 checked portfolio companies on its own site and is named in 12 funding rounds, 5 of them as lead. Its most frequent entry is Seed, 64% of the companies with a known first round. Its largest themes are Healthcare & Biotech (28%), AI & Machine Learning (25%) and Fintech (9%). 89% of its companies are based in United States. It invests most often alongside Techstars, Creative Destruction Lab and Y Combinator.

Counts come from funding rounds that name 2048 Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.

Round figures show recent activity, not 2048 Ventures' whole history. Rounds on record name 11 companies; its own site lists 76. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.

Entry stage

share of companies by the stage of its first round
Show as a table
Share of companies by the stage of the firm's first round
Value
Pre-seed18%
Seed64%
Series A9%
Series B0%
Growth9%

Activity by year

rounds it joined, last 10 years
Show as a table
Funding rounds per year
TotalRounds it led
'1700
'1800
'1900
'2000
'2100
'2200
'2322
'2400
'2500
'26103

Investor profile

percentile among all firms
Portfolio size: 76 companiesRecent activity: 10 rounds in 12 monthsEarly stage: 82% of entries at pre-seed or seedEvidence: 12% of companies confirmed by a roundSector focus: 28% in its largest sectorReach: 5 countriesPortfolio size92th pctRecent activity95th pctEarly stage84th pctEvidence81th pctSector focus46th pctReach78th pct
This firmMedian of all firms
Show as a table
2048 Ventures compared with all firms
MeasurePercentile of all firmsValue
Portfolio size92th76 companies
Recent activity95th10 rounds in 12 months
Early stage84th82% of entries at pre-seed or seed
Evidence81th12% of companies confirmed by a round
Sector focus46th28% in its largest sector
Reach78th5 countries

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
Healthcare & Biotech28%15%
AI & Machine Learning25%18%
Fintech9%12%
E-commerce & Marketplaces5%6%
Food & Agriculture4%3%
Real Estate & Construction4%3%
Cybersecurity4%4%
Industrial & Manufacturing4%7%

Invests most often with

firms sharing its portfolio companies
Show as a table
Co-investors
Share
Techstars10
Creative Destruction Lab6
Y Combinator5
Also Capital3
First Star Ventures3
MGV3
Matchstick Ventures3
Reference Capital3

All co-investors

Its portfolio companies

where they are based, and what their own sites show

Headquarters

Site status

  • Site answers7497%
  • No longer answers00%
  • Points to another company23%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Co-investor network

who it backs companies with, and who they back together
53 shared companies46 shared companies41 shared companies12 shared companies12 shared companies10 shared companies9 shared companies6 shared companies5 shared companies4 shared companies3 shared companies2 shared companies2 shared companies2 shared companies2 shared companiesTechstars: 10 shared companiesTechstars10Creative Destruction Lab: 6 shared companiesCreative Destruction …6Y Combinator: 5 shared companiesY Combinator5Also Capital: 3 shared companiesAlso Capital3First Star Ventures: 3 shared companiesFirst Star Ventures3MGV: 3 shared companiesMGV3Matchstick Ventures: 3 shared companiesMatchstick Ventures3Reference Capital: 3 shared companiesReference Capital3Trajectory Ventures: 3 shared companiesTrajectory Ventures3AIN Ventures: 2 shared companiesAIN Ventures2ARC Capital: 2 shared companiesARC Capital2Actions Capital: 2 shared companiesActions Capital2
Shared portfolio companies with 2048 VenturesFirms that also back companies together

All co-investors or Compare portfolios with Techstars

Compare 2048 Ventures head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Recent portfolio activity

when companies last raised with 2048 Ventures
DateCompanyStage
10 Nov 2026Neobeneobetherapeutics.comSeed
6 Oct 2026Zerosetzeroset.comPre-Seed Led
9 Sept 2026TwoStep Therapeuticstwosteptx.comSeries A
1 Sept 2026Aslan Protectsaslanprotects.comSeed
21 Jul 2026GlossGeniusglossgenius.comSeries C+
29 Jun 2026Nebexnebex.comSeed
19 May 2026Rely Intelligencetryrely.aiSeed Led
11 Mar 2026Broomebroome.aiPre-Seed Led

Round details for 2048 Ventures

Amounts, full round histories and every co-investor in 2048 Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.

See rounds on Fundup AI →

Portfolio

76 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
Abstract Bioabstractbio.comAbstract Bio synthesizes DNA, including gene fragments and variant libraries, and offers related services such as codon optimization.
Healthcare & Biotech
Portfolio page
Aclidaclid.bioAclid provides an automation platform for biosecurity and biosafety compliance
Healthcare & Biotech
Portfolio page
Acorn Financeacornfinance.comAcorn Finance offers financing for contractors and their customers
Fintech
Portfolio page
Aerodomeaerodome.com · United States
CybersecurityAI & Machine Learning
Oct 2023SeedPage + round
Airspace Linkairspacelink.com · United StatesAirspace Link provides drone operations management services, including airspace security, operations management, and air traffic coordination.
AI & Machine LearningAI & Machine Learning
Portfolio page
Almanac Engineeringalmanacengineering.comAlmanac Engineering produces an integrated polymer laser powder bed fusion production center called Primateria
Industrial & Manufacturing
Portfolio page
Arrowarrowhq.comArrow provides a financial operating system for healthcare that streamlines revenue cycle management using collaborative AI
Healthcare & Biotech
Portfolio page
Aslan Protectsaslanprotects.com · United StatesAslan builds technology to overcome national security threats in the digital world
CybersecurityAI & Machine Learning
Sept 2026SeedPage + round
Atlasatlasmotion.com · United StatesAtlas Motion Systems designs and manufactures motors and motion systems for drones and robots.
AI & Machine LearningAI & Machine Learning
Portfolio page
Aviaryaviaryhealth.comAviary Health provides virtual care, rehabilitation, and care management services to health systems and practices.
Healthcare & Biotech
Portfolio page
BioBox Analyticsbiobox.ioBioBox helps biopharma bring institutional knowledge and multi-modal data into an ecosystem for hypothesis testing, decision making, and decision provenance.
Healthcare & Biotech
Portfolio page
Broomebroome.ai · United StatesBroome provides an AI platform for commercial real estate investors to manage their assets and opportunities
Real Estate & ConstructionAI & Machine Learning
Mar 2026Pre-SeedPage + round
Caravel Biocaravel.bioCaravel Bio is developing an automated picolab for the biomolecular frontier
Healthcare & Biotech
Portfolio page
Century Healthcentury.healthCentury Health provides real-world data for medical breakthroughs
Healthcare & Biotech
Portfolio page
Citrus Labscitruslabs.comCitruslabs designs and runs clinical trials and consumer perception studies for consumer health brands.
Healthcare & BiotechFood & Agriculture
Portfolio page
Cobalt portfoliocobaltid.comCobalt ID maps the network of beneficial owners, connected entities, and structural patterns to reveal business risk intelligence.
FintechCybersecurity
Portfolio page
Coding Biocoding.bioThe company builds immunotherapies for cancer patients by testing millions of candidates to find the best therapies.
Healthcare & Biotech
Portfolio page
Colla Healthcollahealth.comColla Health provides mental health services for cancer patients.
Healthcare & Biotech
Portfolio page
ConverseNowconversenow.ai · United StatesConverseNow provides voice ordering solutions for restaurants using artificial intelligence
AI & Machine LearningFood & Agriculture
Portfolio page
CoolRcoolrgroup.comCoolR provides an AI-powered SaaS platform that analyzes images of coolers and freezers to give commercial insights to food and beverage companies.
Food & AgricultureAI & Machine Learning
Portfolio page

About this data

site last read 11 Nov 2026
The homepage of 2048 Ventures, as last read
2048.vc as VCinfo last read it
Site
2048.vc
Last read
11 Nov 2026
Watching since
5 Nov 2026
Rounds since
1 May 2023
Companies checked
76

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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