Investors / United States / LSG Investments
LSG Investments
Venture capital · Harrisburg, PA, United States · North America
LSG Investments is an evergreen venture fund that invests in early-stage life science companies, typically providing capital alongside business advice. It was created in 2002 through legislation allocating Master Tobacco Settlement Act funds to support Pennsylvania's life sciences sector.
Invests inHealthcare & Biotech
In its own wordslife sciencesdrug discoverydiagnosticsmedical deviceshealthcare itmanufacturing
Your fit with LSG Investments
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsLSG Investments lists 18 checked portfolio companies on its own site and is named in 2 funding rounds. Its most frequent entry is Series A, 50% of the companies with a known first round. Its largest themes are Healthcare & Biotech (90%), Industrial & Manufacturing (5%) and Consumer (5%). 100% of its companies are based in United States. It invests most often alongside IndieBio, MemorialCare Innovation Fund and SOSV.
Counts come from funding rounds that name LSG Investments, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not LSG Investments' whole history. Rounds on record name 2 companies; its own site lists 18. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 50% |
| Series B | 50% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 0 | 0 |
| '26 | 2 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 46th | 18 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 80th | 11% of companies confirmed by a round |
| Sector focus | 95th | 90% in its largest sector |
| Reach | 19th | 1 country |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| IndieBio | 2 |
| MemorialCare Innovation Fund | 2 |
| SOSV | 2 |
| UPMC Enterprises | 2 |
| 3E Bioventures Capital | 1 |
| 412 Venture Fund | 1 |
| Accanto Partners | 1 |
| Asset Management Company | 1 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers1689%
- No longer answers00%
- Points to another company211%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 90% | 15% |
| Industrial & Manufacturing | 5% | 7% |
| Consumer | 5% | 3% |
Co-investor network
who it backs companies with, and who they back togetherCompare LSG Investments head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with LSG Investments| Date | Company | Stage |
|---|---|---|
| 6 Aug 2026 | Series B | |
| 25 Feb 2026 | Series A |
Round details for LSG Investments
Amounts, full round histories and every co-investor in LSG Investments' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
18 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Avisi Technologies develops a nanotechnology-enabled device to treat open-angle glaucoma | Healthcare & Biotech | Feb 2026Series A | Page + round | |
| BioLattice Ophthalmics develops an engineered cornea as an alternative to donor cornea for cornea repair and transplant | Healthcare & Biotech | Portfolio page | ||
| Carta Healthcare develops and provides an AI platform for managing and analyzing clinical data for healthcare organizations. | Healthcare & Biotech | Portfolio page | ||
| Chromatan develops and provides continuous column-free chromatography technology for bioprocessing and biomanufacturing | Healthcare & Biotech | Portfolio page | ||
| Forma Medical develops and provides solutions for minimally invasive forefoot surgery. | Healthcare & Biotech | Portfolio page | ||
| Ilico Genetics develops a screening test for early-stage stomach cancer | Healthcare & Biotech | Portfolio page | ||
| Immunomic Therapeutics develops vaccines through its proprietary technology platform, UNITE, which is designed to utilize the body's natural biochemistry to develop vaccines that generate broad immune responses | Healthcare & Biotech | Portfolio page | ||
| The company provides in vitro solutions and services for drug discovery, safety, and environmental testing. | Healthcare & Biotech | Portfolio page | ||
| InnSight Technology develops and manufactures point of care diagnostic devices for analyzing tear fluid to guide disease diagnosis and management | Healthcare & Biotech | Portfolio page | ||
Industrial & ManufacturingConsumer | Portfolio page | |||
Healthcare & Biotech | Portfolio page | |||
| MeduLoc, Inc. develops a flexible, intramedullary fixation platform for fracture fixation. | Healthcare & Biotech | Aug 2026Series B | Page + round | |
| Micro Interventional Devices designs, manufactures and commercializes catheter-based technologies for the treatment of structural heart disease. | Healthcare & Biotech | Portfolio page | ||
| The company develops and provides an AI-powered fall mitigation solution for healthcare facilities | Healthcare & Biotech | Portfolio page | ||
| Saladax Biomedical develops and manufactures therapeutic drug monitoring assays for medications prescribed by psychiatrists and oncologists | Healthcare & Biotech | Portfolio page | ||
| Signature Diagnostics develops noninvasive diagnostics to predict, detect, and understand human disease | Healthcare & Biotech | Portfolio page | ||
| SOLUtion Medical is a specialty pharmaceutical company that develops and supplies reconstitution products with proprietary delivery devices. | Healthcare & Biotech | Portfolio page | ||
| SovaSage develops and provides AI-powered solutions for CPAP therapy, including mask matching, virtual patient setup, and adherence coaching. | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- lsgpa.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 25 Feb 2026
- Companies checked
- 18
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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