Investors / United States / Pappas Capital
Pappas Capital
Venture capital · Research Triangle Park, NC, United States · North America
Pappas Capital is a venture capital and commercial development firm that invests in life science, agriculture and technology companies. It operates through Pappas Ventures, a life science venture arm, Specialized Fund Management, which creates custom investment vehicles, and Translational Medicine, which partners with research universities to develop scientific discoveries.
Invests inHealthcare & BiotechAI & Machine Learning
In its own wordslife sciencesbiotechhealthcareagriculturetechnologydrug development
Your fit with Pappas Capital
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsPappas Capital lists 39 checked portfolio companies on its own site and is named in 2 funding rounds. Its most frequent entry is Series A, 100% of the companies with a known first round. Its largest themes are Healthcare & Biotech (71%), AI & Machine Learning (16%) and Education (2%). 88% of its companies are based in United States. It invests most often alongside Frazier Life Sciences, Hatteras Venture Partners and Mission BioCapital.
Counts come from funding rounds that name Pappas Capital, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Pappas Capital's whole history. Rounds on record name 2 companies; its own site lists 39. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundPappas Capital does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 100% |
| Series B | 0% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 0 | 0 |
| '26 | 2 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 77th | 39 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 64th | 5% of companies confirmed by a round |
| Sector focus | 92th | 71% in its largest sector |
| Reach | 70th | 4 countries |
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 71% | 15% |
| AI & Machine Learning | 16% | 18% |
| Education | 2% | 7% |
| Industrial & Manufacturing | 2% | 7% |
| Robotics & Hardware | 2% | 1% |
| Consumer | 2% | 3% |
| Cybersecurity | 2% | 4% |
| Enterprise Software | 2% | 8% |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| Frazier Life Sciences | 3 |
| Hatteras Venture Partners | 3 |
| Mission BioCapital | 3 |
| NEA | 3 |
| Advent Life Sciences | 2 |
| Berkeley Catalyst Fund | 2 |
| Biovision Ventures | 2 |
| Boxer Capital | 2 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers3795%
- No longer answers00%
- Points to another company25%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Co-investor network
who it backs companies with, and who they back togetherAll co-investors or Compare portfolios with Frazier Life Sciences
Compare Pappas Capital head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Pappas Capital| Date | Company | Stage |
|---|---|---|
| 14 Oct 2026 | Series A | |
| 29 Sept 2026 | Series A |
Round details for Pappas Capital
Amounts, full round histories and every co-investor in Pappas Capital's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
39 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| The company invents and develops genetic medicines with proprietary customized vectors for retinal and pulmonary diseases. | Healthcare & Biotech | Portfolio page | ||
| 5Metis is a novel mode of action and intellectual property development company solving fungicide resistance for growers worldwide by providing scientific research in the field of agriculture. | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| Aer Therapeutics develops a therapy to liquify mucus plugs in the lungs to improve lung health | Healthcare & Biotech | Portfolio page | ||
| Aktis Oncology develops targeted alpha-based radiopharmaceuticals for the treatment of cancer patients. | Healthcare & Biotech | Portfolio page | ||
| Altay Therapeutics develops small molecules to address serious diseases by inhibiting transcription factors | Healthcare & Biotech | Oct 2026Series A | Page + round | |
| Anthera produces and sells vegan cosmetics, including nail care products, made in France. | Consumer | Portfolio page | ||
| Aura Biosciences is a clinical-stage biotechnology company that develops targeted oncology therapies for ocular cancers. | Healthcare & Biotech | Portfolio page | ||
| The company champions for bringing new treatments to patients with serious medical conditions and supports policies that promote innovation and improve patient access. | Healthcare & Biotech | Portfolio page | ||
| BioAtla develops novel therapeutics with improved therapeutic index that are safer and more effective for treating cancer | Healthcare & Biotech | Portfolio page | ||
| Bloodhound Technologies provides real-time personnel location and productivity management solutions | CybersecurityEnterprise Software | Portfolio page | ||
| Borah AI partners with organizations to provide custom AI solutions and generative AI consulting services | AI & Machine LearningHealthcare & Biotech | Portfolio page | ||
| Breye Therapeutics develops novel, orally administered ophthalmology drugs to meet the needs of patients at risk of vision loss. | Healthcare & Biotech | Sept 2026Series A | Page + round | |
Healthcare & Biotech | Portfolio page | |||
| CuraSen Therapeutics rethinks brain disease | Healthcare & Biotech | Portfolio page | ||
| Curis is developing differentiated therapeutics with the goal of improving the lives of cancer patients | Healthcare & Biotech | Portfolio page | ||
| Korsana Biosciences is a biotechnology company that develops therapeutics to reduce the burden of neurodegenerative diseases | Healthcare & Biotech | Portfolio page | ||
| EarthOptics combines advanced field sensors and lab analysis to deliver the most complete view of a soil's potential | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| Embrex develops and manufactures in ovo hatchery vaccination and egg-based vaccine production technology | Healthcare & Biotech | Portfolio page | ||
| The company creates biology-based life science solutions that enhance, improve and protect human, animal and plant life | AI & Machine LearningAI & Machine Learning | Portfolio page | ||
| Enlaza is developing first-in-class covalent protein therapeutics to transform the treatment of cancer and other serious diseases. | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- pappas-capital.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 29 Sept 2026
- Companies checked
- 39
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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