Investors / United States / Longitude Capital
Longitude Capital
Venture capital · Menlo Park, CA, United States · North America
Longitude Capital is a venture growth investor focused on healthcare, making investments in biotechnology, medical technology, and health solutions companies. It invests in both privately held and publicly traded companies using structures such as traditional venture capital, asset spin-outs, recapitalizations, PIPEs, open market purchases, and royalties.
Invests inHealthcare & Biotech
In its own wordshealthcarebiotechnologymedical technologyhealth solutionsventure growthlife sciences
Your fit with Longitude Capital
Four questions about your startup
See how your round matches what it backs, point by point.
Or find every investor that fitsLongitude Capital lists 82 checked portfolio companies on its own site and is named in 4 funding rounds, 1 of them as lead. Its most frequent entry is Series A, 75% of the companies with a known first round. Its largest themes are Healthcare & Biotech (92%), Space & Defense (2%) and Industrial & Manufacturing (1%). 88% of its companies are based in United States. It invests most often alongside RA Capital, Frazier Life Sciences and Foresite Capital.
Counts come from funding rounds that name Longitude Capital, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Longitude Capital's whole history. Rounds on record name 4 companies; its own site lists 82. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundShow as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 75% |
| Series B | 0% |
| Growth | 25% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 2 | 0 |
| '26 | 2 | 1 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 93th | 80 companies |
| Recent activity | 69th | 2 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 59th | 4% of companies confirmed by a round |
| Sector focus | 96th | 92% in its largest sector |
| Reach | 78th | 5 countries |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| RA Capital | 15 |
| Frazier Life Sciences | 9 |
| Foresite Capital | 5 |
| NEA | 5 |
| Endeavour Vision | 4 |
| Omega Funds | 4 |
| Sofinnova | 4 |
| .406 Ventures | 3 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers7591%
- No longer answers00%
- Points to another company79%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 92% | 15% |
| Space & Defense | 2% | 3% |
| Industrial & Manufacturing | 1% | 7% |
| Fintech | 1% | 12% |
| Human Resources | 1% | 1% |
| Food & Agriculture | 1% | 3% |
| E-commerce & Marketplaces | 1% | 6% |
Co-investor network
who it backs companies with, and who they back togetherCompare Longitude Capital head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Longitude Capital| Date | Company | Stage |
|---|---|---|
| 20 May 2026 | Series A | |
| 9 Jan 2026 | Series A Led | |
| 23 Oct 2025 | Series C+ | |
| 12 Mar 2025 | Series A |
Round details for Longitude Capital
Amounts, full round histories and every co-investor in Longitude Capital's rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
82 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
Healthcare & Biotech | Portfolio page | |||
| Alpha-9 Oncology is a clinical stage radiopharmaceutical company advancing a portfolio of molecules to treat cancer cells | Healthcare & Biotech | Portfolio page | ||
| Access TeleCare provides telemedicine services to hospitals and health systems across the US. | Healthcare & Biotech | Portfolio page | ||
| AEON Biopharma is developing a branded biosimilar to BOTOX as a therapeutic botulinum toxin treatment | Healthcare & Biotech | Portfolio page | ||
| AirNexis is developing AN01, a dry powder inhaler for COPD | Healthcare & Biotech | Portfolio page | ||
| Akebia Therapeutics is a fully integrated biopharmaceutical company that works to address complications of kidney disease. | Healthcare & Biotech | Portfolio page | ||
| Alentis Therapeutics is a clinical-stage biotech company that treats cancer and reverses fibrosis by developing anti-Claudin-1 antibody-drug conjugates and monoclonal antibodies | Healthcare & Biotech | Portfolio page | ||
| AllIn Bio develops a precision immunology approach to treating chronic inflammatory disease | Healthcare & Biotech | Portfolio page | ||
| Amarin is a global pharmaceutical company that has developed and is pursuing additional treatments to help address cardiovascular disease. | Healthcare & Biotech | Portfolio page | ||
| Ambros Therapeutics is a clinical-stage biotechnology company focused on the development of innovative and transformative medicines for diseases with a high unmet medical need. | Healthcare & Biotech | Portfolio page | ||
Food & Agriculture | Portfolio page | |||
| Aptus Housing Finance Ltd is a Home Loan Company that addresses the housing finance needs of self-employed, low and middle-income families | FintechHuman Resources | Portfolio page | ||
| Assembly Biosciences is developing novel therapies for serious viral and liver diseases. | Healthcare & Biotech | Portfolio page | ||
E-commerce & MarketplacesSpace & Defense | Portfolio page | |||
| Aviceda Therapeutics develops novel therapies to improve the lives of patients with immune-mediated diseases | Healthcare & Biotech | Portfolio page | ||
Healthcare & Biotech | Portfolio page | |||
| The company is harnessing the biology of human aging to develop new therapies for cardiometabolic diseases | Healthcare & Biotech | Portfolio page | ||
| cAMPfield Therapeutics is a clinical-stage biopharmaceutical company developing oral medicines for inflammatory diseases | Healthcare & Biotech | May 2026Series A | Page + round | |
| Ceribell develops and provides point-of-care EEG products for intensive care units, emergency departments, and neurology | Healthcare & Biotech | Portfolio page | ||
| CG Oncology develops and delivers bladder-sparing immunotherapies for bladder cancer | Healthcare & Biotech | Portfolio page |
About this data
site last read 8 Nov 2026- Site
- longitudecapital.com
- Last read
- 8 Nov 2026
- Watching since
- 6 Nov 2026
- Rounds since
- 12 Mar 2025
- Companies checked
- 82
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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