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Investors / United States / Omega Funds

Omega Funds

Venture capital · Boston, MA, United States · North America

omegafunds.comTakes pitches from founders

Omega Funds invests in founders and companies developing products and platforms in medicine, and states it has helped bring 56 products to patients. It operates from offices in Boston and Geneva and manages a series of numbered funds.

Invests inHealthcare & Biotech

In its own wordsbiotechtherapeuticsoncologyimmunologyrare diseasesprecision medicine

Your fit with Omega Funds

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87portfolio companies
10funding rounds on record1 led
8rounds, last 12 months
$100M or moretypical round it comes in at
Series Bmost frequent entry

Omega Funds lists 87 checked portfolio companies on its own site and is named in 10 funding rounds, 1 of them as lead. Its most frequent entry is Series B, 60% of the companies with a known first round. Its largest themes are Healthcare & Biotech (84%), Fintech (2%) and AI & Machine Learning (2%). 65% of its companies are based in United States. It invests most often alongside RA Capital, Atlas Venture and Jeito Capital.

Counts come from funding rounds that name Omega Funds, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.

Round figures show recent activity, not Omega Funds' whole history. Rounds on record name 10 companies; its own site lists 87. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.

Entry stage

share of companies by the stage of its first round

Omega Funds does not state its stages on its site, so only what it does is shown.

Show as a table
Share of companies by the stage of the firm's first round
Value
Pre-seed0%
Seed0%
Series A40%
Series B60%
Growth0%

Activity by year

rounds it joined, last 10 years
Show as a table
Funding rounds per year
TotalRounds it led
'1700
'1800
'1900
'2000
'2100
'2200
'2300
'2400
'2530
'2671

Investor profile

percentile among all firms
Portfolio size: 86 companiesRecent activity: 8 rounds in 12 monthsEarly stage: 0% of entries at pre-seed or seedEvidence: 9% of companies confirmed by a roundSector focus: 84% in its largest sectorReach: 12 countriesPortfolio size94th pctRecent activity93th pctEarly stage54th pctEvidence75th pctSector focus94th pctReach97th pct
This firmMedian of all firms
Show as a table
Omega Funds compared with all firms
MeasurePercentile of all firmsValue
Portfolio size94th86 companies
Recent activity93th8 rounds in 12 months
Early stage54th0% of entries at pre-seed or seed
Evidence75th9% of companies confirmed by a round
Sector focus94th84% in its largest sector
Reach97th12 countries

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
Healthcare & Biotech84%15%
Fintech2%12%
AI & Machine Learning2%18%
Media & Entertainment2%4%
Industrial & Manufacturing2%7%
Education1%7%
Enterprise Software1%8%
E-commerce & Marketplaces1%6%

Invests most often with

firms sharing its portfolio companies
Show as a table
Co-investors
Share
RA Capital7
Atlas Venture6
Jeito Capital6
ARCH Venture Partners5
Aisling Capital5
Frazier Life Sciences5
NEA5
Foresite Capital4

All co-investors

Its portfolio companies

where they are based, and what their own sites show

Headquarters

Site status

  • Site answers7890%
  • No longer answers00%
  • Points to another company910%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Co-investor network

who it backs companies with, and who they back together
22 shared companies17 shared companies15 shared companies12 shared companies11 shared companies10 shared companies10 shared companies9 shared companies9 shared companies8 shared companies8 shared companies7 shared companies6 shared companies6 shared companies6 shared companies6 shared companies5 shared companies5 shared companies5 shared companies5 shared companies5 shared companies5 shared companies5 shared companies5 shared companiesRA Capital: 7 shared companiesRA Capital7Atlas Venture: 6 shared companiesAtlas Venture6Jeito Capital: 6 shared companiesJeito Capital6ARCH Venture Partners: 5 shared companiesARCH Venture Partners5Aisling Capital: 5 shared companiesAisling Capital5Frazier Life Sciences: 5 shared companiesFrazier Life Sciences5NEA: 5 shared companiesNEA5Foresite Capital: 4 shared companiesForesite Capital4Longitude Capital: 4 shared companiesLongitude Capital4Novartis Venture Fund: 4 shared companiesNovartis Venture Fund4Pivotal Life Sciences: 4 shared companiesPivotal Life Sciences4Altamont Pharmaceutical Holdings: 3 shared companiesAltamont Pharmaceutic…3
Shared portfolio companies with Omega FundsFirms that also back companies together

All co-investors or Compare portfolios with RA Capital

Compare Omega Funds head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Recent portfolio activity

when companies last raised with Omega Funds
DateCompanyStage
11 Aug 2026Vaderis Therapeuticsvaderis.comSeries B
4 May 2026Windward Biowindwardbio.comSeries B
4 Feb 2026Third Arc Biothirdarcbio.comSeries A
14 Jan 2026calderatx.comcalderatx.comSeries A
8 Jan 2026Alveus Therapeuticsalveustx.comSeries A
7 Jan 2026spiro-medical.comspiro-medical.comSeries A
1 Dec 2025Protegoprotegobio.comSeries B
8 Sept 2025NRG Therapeuticsnrgtherapeutics.comSeries B

Round details for Omega Funds

Amounts, full round histories and every co-investor in Omega Funds' rounds are on Fundup AI. VCinfo covers investors and their portfolios.

See rounds on Fundup AI →

Portfolio

87 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
Acruxacrux.com.au · AustraliaAcrux develops and commercialises a pipeline of topically applied pharmaceutical products.
Healthcare & Biotech
Portfolio page
Aerium Therapeuticsaeriumtx.com
Portfolio page
Alleviant Medicalalleviantmedical.com · United StatesAlleviant Medical is currently evaluating interatrial shunt therapy in heart failure patients through clinical trials.
Healthcare & Biotech
Portfolio page
Omega Fund VIIIaltareturn.com · United States
FintechAI & Machine Learning
Portfolio page
Alumisalumis.com · United StatesAlumis Inc is focused on immune-mediated disease therapies
Healthcare & Biotech
Portfolio page
Alveus Therapeuticsalveustx.com · United StatesAlveus Therapeutics develops treatments for obesity and weight loss maintenance
Healthcare & Biotech
Jan 2026Series APage + round
Aquariusaquariustechnologies.com · United StatesAquarius designs and supplies aeration systems for wastewater treatment
Industrial & ManufacturingEnterprise Software
Portfolio page
Arcutisarcutis.comArcutis Biotherapeutics develops targeted therapies for chronic immune-driven skin diseases.
Healthcare & Biotech
Portfolio page
Arrakisarrakistx.comArrakis Therapeutics creates genetic medicines, specifically RNA-targeted small molecules, to treat various diseases.
Healthcare & Biotech
Portfolio page
artbio.comartbio.com · NorwayARTBIO develops alpha radioligand therapies for cancer treatment.
Healthcare & Biotech
Jul 2025Series BFunding round
Ateaateapharma.com · United StatesAtea Pharmaceuticals is a late-stage clinical biopharmaceutical company engaged in the discovery and development of oral antiviral therapeutics for serious viral diseases.
Healthcare & Biotech
Portfolio page
Aviceda Therapeuticsavicedarx.comAviceda Therapeutics develops novel therapies to improve the lives of patients with immune-mediated diseases
Healthcare & Biotech
Portfolio page
Beam Therapeuticsbeamtx.com · United StatesBeam Therapeutics is a company that develops precision genetic medicines using base editing technology
Healthcare & Biotech
Portfolio page
Beta Bionicsbetabionics.comBeta Bionics develops an insulin delivery system that automatically learns and adapts to a user's needs
Healthcare & Biotech
Portfolio page
Bioinvent Internationalbioinvent.com
Portfolio page
BBOTbridgebiooncology.com · United StatesThe company aims to inhibit the active ON state of RAS signaling in cancer, using expert understanding of RAS signaling biology to inform rational drug design.
Healthcare & Biotech
Portfolio page
calderatx.comcalderatx.com · United StatesCaldera Therapeutics is a clinical-stage biotechnology company developing a potential first-in-class bispecific antibody for inflammatory bowel disease and other immune-mediated diseases.
Healthcare & Biotech
Jan 2026Series APage + round
Callio Therapeuticscalliotx.com · United StatesCallio Therapeutics is a global, clinical-stage biotechnology company developing dual-payload antibody-drug conjugates (ADCs) to address the key limitation of current therapies, resistance.
Healthcare & Biotech
Portfolio page
CatalYmcatalym.com · GermanyCatalYm is developing a safe and efficacious immune therapy for solid tumors.
Healthcare & Biotech
Portfolio page
CDR-Lifecdr-life.comCDR-Life develops innovative treatments for cancer and autoimmune diseases through its T cell engager platform, M-gager
Healthcare & Biotech
Portfolio page

About this data

site last read 11 Nov 2026
The homepage of Omega Funds, as last read
omegafunds.com as VCinfo last read it
Site
omegafunds.com
Last read
11 Nov 2026
Watching since
5 Nov 2026
Rounds since
29 Jul 2025
Companies checked
87

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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