Investors / United States / Pivotal Life Sciences
Pivotal Life Sciences
Venture capital · San Francisco, CA, United States · North America
Pivotal Life Sciences is a global healthcare investment platform that provides capital to companies developing therapeutic products and technologies for unmet medical needs. It operates through Pivotal bioVenture Partners in North America and Europe, Pivotal bioVenture Partners (China) focused on venture building in Greater China, and a public equity team investing in listed life sciences companies.
Invests inHealthcare & Biotech
In its own wordstherapeuticslife scienceshealthcarebiotechpublic equityventure building
Your fit with Pivotal Life Sciences
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See how your round matches what it backs, point by point.
Or find every investor that fitsPivotal Life Sciences lists 33 checked portfolio companies on its own site and is named in 5 funding rounds, 1 of them as lead. Its most frequent entry is Series A, 60% of the companies with a known first round. Its largest theme is Healthcare & Biotech (100%). 88% of its companies are based in United States. It invests most often alongside RA Capital, SR One and Frazier Life Sciences.
Counts come from funding rounds that name Pivotal Life Sciences, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.
Round figures show recent activity, not Pivotal Life Sciences' whole history. Rounds on record name 5 companies; its own site lists 33. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.
Entry stage
share of companies by the stage of its first roundPivotal Life Sciences does not state its stages on its site, so only what it does is shown.
Show as a table
| Value | |
|---|---|
| Pre-seed | 0% |
| Seed | 0% |
| Series A | 60% |
| Series B | 40% |
| Growth | 0% |
Activity by year
rounds it joined, last 10 yearsShow as a table
| Total | Rounds it led | |
|---|---|---|
| '17 | 0 | 0 |
| '18 | 0 | 0 |
| '19 | 0 | 0 |
| '20 | 0 | 0 |
| '21 | 0 | 0 |
| '22 | 0 | 0 |
| '23 | 0 | 0 |
| '24 | 0 | 0 |
| '25 | 2 | 1 |
| '26 | 3 | 0 |
Investor profile
percentile among all firmsShow as a table
| Measure | Percentile of all firms | Value |
|---|---|---|
| Portfolio size | 71th | 33 companies |
| Recent activity | 82th | 4 rounds in 12 months |
| Early stage | 54th | 0% of entries at pre-seed or seed |
| Evidence | 67th | 6% of companies confirmed by a round |
| Sector focus | 100th | 100% in its largest sector |
| Reach | 70th | 4 countries |
Invests most often with
firms sharing its portfolio companiesShow as a table
| Share | |
|---|---|
| RA Capital | 10 |
| SR One | 6 |
| Frazier Life Sciences | 5 |
| ARCH Venture Partners | 4 |
| Omega Funds | 4 |
| Samsara BioCapital | 4 |
| Bay City Capital | 3 |
| F-Prime Capital | 3 |
Its portfolio companies
where they are based, and what their own sites showSite status
- Site answers3297%
- No longer answers00%
- Points to another company13%
- Parked or sold domain00%
A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.
Investment themes
share of its checked companiesThis firmAll checked companies
Show as a table
| This firm | All checked companies | |
|---|---|---|
| Healthcare & Biotech | 100% | 15% |
Co-investor network
who it backs companies with, and who they back togetherCompare Pivotal Life Sciences head to head
portfolio size, rounds, entry stages, themes and the companies both backThree or more firms at once: portfolio overlap.
Recent portfolio activity
when companies last raised with Pivotal Life Sciences| Date | Company | Stage |
|---|---|---|
| 16 Oct 2026 | Series A | |
| 22 Jul 2026 | Series B | |
| 4 May 2026 | Series B | |
| 17 Dec 2025 | Series A | |
| 9 Jun 2025 | Series A Led |
Round details for Pivotal Life Sciences
Amounts, full round histories and every co-investor in Pivotal Life Sciences' rounds are on Fundup AI. VCinfo covers investors and their portfolios.
Portfolio
33 companies checked against their own sites| Company | What it does | Themes | First round with it | Evidence |
|---|---|---|---|---|
| Addition Therapeutics is advancing a pipeline of therapeutics to deliver functional cures for patients with severe lifelong diseases | Healthcare & Biotech | Dec 2025Series A | Page + round | |
| Aligos Therapeutics develops therapies for liver and viral diseases | Healthcare & Biotech | Portfolio page | ||
| Arcutis Biotherapeutics develops targeted therapies for chronic immune-driven skin diseases. | Healthcare & Biotech | Portfolio page | ||
| Avalyn Pharma develops inhaled therapies to treat rare respiratory diseases, including pulmonary fibrosis and other interstitial lung diseases. | Healthcare & Biotech | Portfolio page | ||
| The company is harnessing the biology of human aging to develop new therapies for cardiometabolic diseases | Healthcare & Biotech | Portfolio page | ||
| Bolt Biotherapeutics develops treatments for cancer | Healthcare & Biotech | Portfolio page | ||
| Crystalys Therapeutics develops new therapeutics to address unmet medical needs, specifically for people living with gout. | Healthcare & Biotech | Jul 2026Series B | Funding round | |
| Helus Pharma develops novel serotonergic agonists for the treatment of mental health conditions | Healthcare & Biotech | Portfolio page | ||
| Engrail Therapeutics is a clinical-stage pharmaceutical company that develops new treatments for disorders of the nervous system. | Healthcare & Biotech | Portfolio page | ||
| Estuary Bio is developing gene therapies to treat autosomal dominant polycystic kidney disease (ADPKD) | Healthcare & Biotech | Oct 2026Series A | Funding round | |
| Evommune discovers and develops innovative therapies that target key drivers of chronic inflammatory disease. | Healthcare & Biotech | Portfolio page | ||
Healthcare & Biotech | Portfolio page | |||
| Fusion Pharmaceuticals develops targeted alpha therapeutics for precision medicine to treat cancers | Healthcare & Biotech | Portfolio page | ||
| Gossamer Bio is a clinical-stage biopharmaceutical company focused on the development of its investigational drug product, seralutinib, for the treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD). | Healthcare & Biotech | Portfolio page | ||
| GRAIL develops and offers a multi-cancer early detection test using a blood sample. | Healthcare & Biotech | Portfolio page | ||
| Harmony Biosciences develops medicines for patients with unmet medical needs | Healthcare & Biotech | Portfolio page | ||
| HotSpot Therapeutics is pioneering a new approach to allosteric drug discovery for the treatment of autoimmune disease | Healthcare & Biotech | Portfolio page | ||
| The company develops therapeutic candidates for cancer treatment | Healthcare & Biotech | Portfolio page | ||
| IO Biotech develops therapeutic cancer vaccines | Healthcare & Biotech | Portfolio page | ||
| LB Pharmaceuticals is developing medicines for brain disorders | Healthcare & Biotech | Portfolio page |
About this data
site last read 5 Nov 2026- Site
- pivotallifesciences.com
- Last read
- 5 Nov 2026
- Watching since
- 5 Nov 2026
- Rounds since
- 9 Jun 2025
- Companies checked
- 33
Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.
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