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Investors / United States / Phase Two Ventures

Phase Two Ventures

Venture capital · San Diego, CA, United States · North America

phasetwo.vcTakes pitches from founders

Phase Two Ventures is a seed venture fund based in San Diego that invests in early-stage life science tools, platform technologies, and AI x Bio. It provides capital, coaching, and support to pre-seed and seed founders, drawing on partners' operating experience founding and scaling life science companies.

Invests inHealthcare & Biotech

In its own wordslife science toolsplatform technologiesai x biomulti-omicssynthetic biologycell and gene therapy

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14portfolio companies
0funding rounds on record
Pre-seed to Seedstages it states

Phase Two Ventures lists 14 checked portfolio companies on its own site. Its largest theme is Healthcare & Biotech (100%). 89% of its companies are based in United States. It invests most often alongside Creative Destruction Lab, Illumina Ventures and IndieBio.

No funding round on record names Phase Two Ventures yet, so the figures come from its portfolio page.

Round figures show recent activity, not Phase Two Ventures' whole history. Rounds on record name 0 companies; its own site lists 14. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.

Investor profile

percentile among all firms
Portfolio size: 13 companiesRecent activity: 0 rounds in 12 monthsEarly stage: 0% of entries at pre-seed or seedEvidence: 0% of companies confirmed by a roundSector focus: 100% in its largest sectorReach: 2 countriesPortfolio size33th pctRecent activity46th pctEarly stage54th pctEvidence52th pctSector focus100th pctReach42th pct
This firmMedian of all firms
Show as a table
Phase Two Ventures compared with all firms
MeasurePercentile of all firmsValue
Portfolio size33th13 companies
Recent activity46th0 rounds in 12 months
Early stage54th0% of entries at pre-seed or seed
Evidence52th0% of companies confirmed by a round
Sector focus100th100% in its largest sector
Reach42th2 countries

Its portfolio companies

where they are based, and what their own sites show

Headquarters

Site status

  • Site answers14100%
  • No longer answers00%
  • Points to another company00%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
Healthcare & Biotech100%15%

Compare Phase Two Ventures head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Portfolio

14 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
Acurionacurionhealth.com · United StatesAcurion develops and provides a technology called OncoGaze that delivers genomic insights to help oncologists make precision therapy decisions for cancer patients
Healthcare & Biotech
Portfolio page
Andson Biotechandsonbiotech.com · United StatesThe company simplifies mass spec sample preparation
Healthcare & Biotech
Portfolio page
Arima Genomicsarimagenomics.comArima Genomics is building DNA-based cancer diagnostics that bring sequence and structure together to find more of what drives disease
Healthcare & Biotech
Portfolio page
Augment Biologicsaugmentbiologics.comAugment Biologics is the first and only AI-powered glycoprotein design company.
Healthcare & Biotech
Portfolio page
Defined Biosciencedefinedbioscience.comDefined Bioscience develops and sells serum-free stem cell media and supporting reagents for cell culture.
Healthcare & Biotech
Portfolio page
Exthymic Corporationexthymic.com · United StatesThe company develops technologies to manage patient variability and make local production of cell therapies possible
Healthcare & Biotech
Portfolio page
GelTech Labsgeltechlabs.comGelTech Labs provides automated lab services for research and development of soft biomaterials.
Healthcare & Biotech
Portfolio page
Lynx Biolynx.bio · United StatesLynx Bio is a biotech company that develops immunotherapies using a multi-omic platform
Healthcare & Biotech
Portfolio page
Morphos Biosciencemorphos.bio
Portfolio page
NanoCellect Biomedicalnanocellect.com · United StatesNanoCellect Biomedical develops and sells microfluidic cell sorters for gentle sorting of cells.
Healthcare & Biotech
Portfolio page
Navega Therapeuticsnavegatx.com · United StatesNavega Therapeutics develops gene therapies for chronic pain and precision pain management.
Healthcare & Biotech
Portfolio page
Novoron Biosciencenovoron.com · USANovoron Bioscience develops innovative therapies to restore independence and improve patient's lives by pioneering lipoprotein-receptor drug development to repair damage and degeneration of the brain, spinal cord and beyond.
Healthcare & Biotech
Portfolio page
Potato AIreadysetpotato.com · United StatesPotato builds AI-native software that helps scientists research methods, build protocols, design experiments, and improve plate-based assays in one connected workspace.
Healthcare & Biotech
Portfolio page
RyboDynrybodyn.com · United StatesRybodyn develops immunotherapies by unlocking the dark proteome with its proprietary technology.
Healthcare & Biotech
Portfolio page

About this data

site last read 5 Nov 2026
The homepage of Phase Two Ventures, as last read
phasetwo.vc as VCinfo last read it
Site
phasetwo.vc
Last read
5 Nov 2026
Watching since
6 Nov 2026
Companies checked
14

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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