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Investors / United States / Twelve Below

Twelve Below

Venture capital · New York City, NY, United States · North America

twelvebelow.co

Twelve Below is a venture capital firm based in New York City that invests early, typically as a lead investor in rounds before a Series A. It describes itself as generalist by nature and focuses on founders it sees as shaping the future.

Invests inAI & Machine LearningHealthcare & BiotechFintech

In its own wordspre-seedseedearly-stagegeneralist

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36portfolio companies
8funding rounds on record1 led
7rounds, last 12 months
$20M to $100Mtypical round it comes in at
Series Amost frequent entry

Twelve Below lists 36 checked portfolio companies on its own site and is named in 8 funding rounds, 1 of them as lead. Its most frequent entry is Series A, 63% of the companies with a known first round. Its largest themes are AI & Machine Learning (23%), Healthcare & Biotech (22%) and Fintech (17%). 95% of its companies are based in United States. It invests most often alongside Lerer Hippeau, Y Combinator and 2048 Ventures.

Counts come from funding rounds that name Twelve Below, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.

Round figures show recent activity, not Twelve Below's whole history. Rounds on record name 8 companies; its own site lists 36. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.

Entry stage

share of companies by the stage of its first round
Show as a table
Share of companies by the stage of the firm's first round
Value
Pre-seed0%
Seed25%
Series A63%
Series B13%
Growth0%

Activity by year

rounds it joined, last 10 years
Show as a table
Funding rounds per year
TotalRounds it led
'1700
'1800
'1900
'2000
'2100
'2200
'2300
'2400
'2510
'2671

Investor profile

percentile among all firms
Portfolio size: 37 companiesRecent activity: 7 rounds in 12 monthsEarly stage: 25% of entries at pre-seed or seedEvidence: 16% of companies confirmed by a roundSector focus: 23% in its largest sectorReach: 2 countriesPortfolio size75th pctRecent activity91th pctEarly stage60th pctEvidence87th pctSector focus29th pctReach42th pct
This firmMedian of all firms
Show as a table
Twelve Below compared with all firms
MeasurePercentile of all firmsValue
Portfolio size75th37 companies
Recent activity91th7 rounds in 12 months
Early stage60th25% of entries at pre-seed or seed
Evidence87th16% of companies confirmed by a round
Sector focus29th23% in its largest sector
Reach42th2 countries

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
AI & Machine Learning23%18%
Healthcare & Biotech22%15%
Fintech17%12%
Enterprise Software10%8%
Education7%7%
Legal & Compliance5%2%
Real Estate & Construction3%3%
Industrial & Manufacturing2%7%

Invests most often with

firms sharing its portfolio companies
Show as a table
Co-investors
Share
Lerer Hippeau3
Y Combinator3
2048 Ventures2
Expa2
Factorial Capital2
Founder Collective2
Four Acres Capital2
Ground Up Ventures2

All co-investors

Its portfolio companies

where they are based, and what their own sites show

Headquarters

Site status

  • Site answers3597%
  • No longer answers00%
  • Points to another company13%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Co-investor network

who it backs companies with, and who they back together
270 shared companies27 shared companies15 shared companies11 shared companies10 shared companies9 shared companies8 shared companies7 shared companies7 shared companies6 shared companies5 shared companies5 shared companies5 shared companies4 shared companies4 shared companies4 shared companies4 shared companies3 shared companies3 shared companies3 shared companies2 shared companies2 shared companiesLerer Hippeau: 3 shared companiesLerer Hippeau3Y Combinator: 3 shared companiesY Combinator32048 Ventures: 2 shared companies2048 Ventures2Expa: 2 shared companiesExpa2Factorial Capital: 2 shared companiesFactorial Capital2Founder Collective: 2 shared companiesFounder Collective2Four Acres Capital: 2 shared companiesFour Acres Capital2Ground Up Ventures: 2 shared companiesGround Up Ventures2Inspired Capital: 2 shared companiesInspired Capital2Transformation Capital: 2 shared companiesTransformation Capital2Transpose Platform: 2 shared companiesTranspose Platform2Union Square Ventures: 2 shared companiesUnion Square Ventures2
Shared portfolio companies with Twelve BelowFirms that also back companies together

All co-investors or Compare portfolios with Lerer Hippeau

Compare Twelve Below head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Recent portfolio activity

when companies last raised with Twelve Below
DateCompanyStage
29 Oct 2026ShareWillowsharewillow.comSeed
1 Sept 2026Odysseyodysseyenergysolutions.comSeries B
1 Jun 2026Boardboard.funSeries A
28 May 2026Solsticesolsticehealth.coSeries A
27 May 2026solsticewi.comsolsticewi.comSeries A
17 Mar 2026Conduit Healthconduithealth.comSeries A
26 Jan 2026Barnwell Biobarnwellbio.comSeed Led
29 Oct 2025Aryaaryahealth.aiSeries A

Round details for Twelve Below

Amounts, full round histories and every co-investor in Twelve Below's rounds are on Fundup AI. VCinfo covers investors and their portfolios.

See rounds on Fundup AI →

Portfolio

36 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
Architect Financialarchitect.co · United StatesThe company operates a derivatives exchange for trading futures and options on GPU rental prices, metals, energy, and power
FintechAI & Machine Learning
Portfolio page
Aryaaryahealth.ai · United StatesArya Health automates non-clinical administration for healthcare organizations using AI.
Healthcare & Biotech
Oct 2025Series APage + round
Astonastonpower.com · United StatesAston delivers power capacity for complex workloads, including generation, transmission, storage, and software for data centers.
EducationIndustrial & Manufacturing
Portfolio page
Barnwell Biobarnwellbio.com · United StatesBarnwell Bio analyzes environmental samples to uncover insights into animal health and behavior.
AI & Machine LearningHealthcare & Biotech
Jan 2026SeedPage + round
Boardboard.fun · CanadaThe company sells a face-to-face game console and related accessories.
Enterprise SoftwareConsumer
Jun 2026Series AFunding round
Accruebyaccrue.com · United StatesAccrue provides a platform for brands to embed financial products into the customer experience, allowing customers to fund, earn, and spend while driving engagement and loyalty.
FintechLegal & Compliance
Portfolio page
Caladancaladan.bio · United StatesCaladan develops and provides biomanufacturing technology and infrastructure powered by automation, sensors, and artificial intelligence.
Healthcare & Biotech
Portfolio page
Conduit Healthconduithealth.com · United StatesConduit Health delivers daily living supplies, such as incontinence and mobility products, to patients, with costs covered by insurance.
Healthcare & Biotech
Mar 2026Series APage + round
Dispatchdispatch.io · United StatesDispatch provides a data orchestration platform for wealth and asset managers to connect their tech stack and accelerate revenue-critical workflows.
FintechFintech
Portfolio page
Draftboarddraftboard.comDraftboard maps a user's network to show who knows who and find potential warm introductions to target accounts
AI & Machine LearningEnterprise Software
Portfolio page
EdotEnvedotenv.comEdotEnv builds software for financial time-series data using financial markets
FintechEnterprise Software
Portfolio page
Fort Healthforthealth.com · United StatesFort Health provides virtual mental health services for children and adolescents
Healthcare & Biotech
Portfolio page
Lemmagetlemma.com · United StatesThe company provides business banking services to healthcare companies.
Healthcare & BiotechFintech
Portfolio page
Solarigetsolari.comSolari provides infrastructure for AI agents, including browsers, sandboxes, and desktops, through a single API.
AI & Machine LearningCybersecurity
Portfolio page
Headroomheadroom.comHeadroom provides a platform to manage and automate business processes and workflows.
Enterprise SoftwareAI & Machine Learning
Portfolio page
Health Universehealthuniverse.com · United StatesHealth Universe provides a platform to run health AI models, agents, and workflows
Healthcare & Biotech
Portfolio page
Immunaraimmunara.ai
Healthcare & BiotechAI & Machine Learning
Portfolio page
Indie Healthindie.healthIndie Health provides a front desk operating system for high-volume medical practices to manage patient interactions and administrative tasks.
Healthcare & Biotech
Portfolio page
Mentomento.coMento provides performance coaching for leaders and teams using a platform with AI-driven tools and expert coaches.
EducationHuman Resources
Portfolio page
Nomenome.bioNome provides genetic medicine development as a service for rare disease families, foundations, and health systems
Healthcare & Biotech
Portfolio page

About this data

site last read 10 Nov 2026
The homepage of Twelve Below, as last read
twelvebelow.co as VCinfo last read it
Site
twelvebelow.co
Last read
10 Nov 2026
Watching since
5 Nov 2026
Rounds since
29 Oct 2025
Companies checked
36

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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