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Investors / United States / Arboretum Ventures

Arboretum Ventures

Venture capital · Ann Arbor, MI, United States · North America

arboretumvc.comTakes pitches from founders

Arboretum Ventures is a healthcare venture capital firm based in Ann Arbor, Michigan, founded in 2002. It invests in early-stage healthcare companies and reports roughly $1B under management across six funds.

Invests inHealthcare & Biotech

In its own wordshealthcaremedical devicesdiagnosticslife sciences toolstech-enabled carepharma adjacencies

Your fit with Arboretum Ventures

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32portfolio companies
3funding rounds on record2 led
1rounds, last 12 months
$20M to $100Mtypical round it comes in at
Series Bmost frequent entry

Arboretum Ventures lists 32 checked portfolio companies on its own site and is named in 3 funding rounds, 2 of them as lead. Its most frequent entry is Series B, 67% of the companies with a known first round. Its largest themes are Healthcare & Biotech (97%) and Industrial & Manufacturing (3%). 100% of its companies are based in United States. It invests most often alongside Hatteras Venture Partners, Western Technology Investment and Lightstone Ventures.

Counts come from funding rounds that name Arboretum Ventures, complete from mid-2025: earlier rounds appear only when they were reported later. Round amounts and full round histories are on Fundup AI.

Round figures show recent activity, not Arboretum Ventures' whole history. Rounds on record name 3 companies; its own site lists 32. Funding rounds are complete from mid-2025, so counts and the yearly trend undercount a firm that invested before then. The portfolio, themes and places come from its own site and are not affected.

Entry stage

share of companies by the stage of its first round
Show as a table
Share of companies by the stage of the firm's first round
Value
Pre-seed0%
Seed0%
Series A0%
Series B67%
Growth33%

Activity by year

rounds it joined, last 10 years
Show as a table
Funding rounds per year
TotalRounds it led
'1700
'1800
'1900
'2000
'2100
'2200
'2300
'2400
'2521
'2611

Investor profile

percentile among all firms
Portfolio size: 32 companiesRecent activity: 1 rounds in 12 monthsEarly stage: 0% of entries at pre-seed or seedEvidence: 6% of companies confirmed by a roundSector focus: 97% in its largest sectorReach: 1 countryPortfolio size70th pctRecent activity59th pctEarly stage54th pctEvidence68th pctSector focus97th pctReach19th pct
This firmMedian of all firms
Show as a table
Arboretum Ventures compared with all firms
MeasurePercentile of all firmsValue
Portfolio size70th32 companies
Recent activity59th1 rounds in 12 months
Early stage54th0% of entries at pre-seed or seed
Evidence68th6% of companies confirmed by a round
Sector focus97th97% in its largest sector
Reach19th1 country

Invests most often with

firms sharing its portfolio companies
Show as a table
Co-investors
Share
Hatteras Venture Partners4
Western Technology Investment4
Lightstone Ventures3
ID Ventures2
Invest Michigan2
Longitude Capital2
Santé Ventures2
cultivate(MD)2

All co-investors

Its portfolio companies

where they are based, and what their own sites show

Headquarters

Site status

  • Site answers3094%
  • No longer answers00%
  • Points to another company26%
  • Parked or sold domain00%

A site that stops answering three checks in a row is counted as no longer answering; that is not proof of closure. A site that points to another company is often an acquisition.

Investment themes

share of its checked companies

This firmAll checked companies

Show as a table
Investment themes
This firmAll checked companies
Healthcare & Biotech97%15%
Industrial & Manufacturing3%7%

Compare Arboretum Ventures head to head

portfolio size, rounds, entry stages, themes and the companies both back

Three or more firms at once: portfolio overlap.

Recent portfolio activity

when companies last raised with Arboretum Ventures
DateCompanyStage
25 Mar 2026Endogenexendogenex.comSeries C+ Led
4 Sept 2025Boomerangtrial.comboomerangtrial.comSeries B Led
13 Aug 2025reprievecardio.comreprievecardio.comSeries B

Round details for Arboretum Ventures

Amounts, full round histories and every co-investor in Arboretum Ventures' rounds are on Fundup AI. VCinfo covers investors and their portfolios.

See rounds on Fundup AI →

Portfolio

32 companies checked against their own sites
CompanyWhat it doesThemesFirst round with itEvidence
Akadeum Life Sciencesakadeum.com · United StatesAkadeum Life Sciences develops and provides cell separation technology for therapeutic applications
Healthcare & Biotech
Portfolio page
Allay Therapeuticsallaytx.comAllay Therapeutics develops technology for localized pain management.
Healthcare & Biotech
Portfolio page
ArborMetrixarbormetrix.comArborMetrix provides a technological framework for quality improvement in healthcare
Healthcare & Biotech
Portfolio page
AtaCor Medicalatacor.com · United StatesAtaCor Medical designs novel extravascular defibrillation leads and deployment systems for cardiac rhythm management
Healthcare & Biotech
Portfolio page
Avation Medicalavation.comAvation Medical develops and offers a wearable at-home treatment for overactive bladder
Healthcare & Biotech
Portfolio page
BioIQbioiq.com
Healthcare & Biotech
Portfolio page
Boomerang Medicalboomerangmedical.com · United StatesBoomerang Medical is developing a bioelectric neuromodulation technology to treat autoimmune disease symptoms
Healthcare & Biotech
Portfolio page
Boomerangtrial.comboomerangtrial.com · United StatesThe company is conducting a clinical study to test a new treatment for bowel urgency symptoms in adults with ulcerative colitis.
Healthcare & Biotech
Sept 2025Series BFunding round
BrightSpecbrightspec.comBrightSpec develops and provides molecular rotational resonance spectroscopy products and solutions
Healthcare & BiotechIndustrial & Manufacturing
Portfolio page
Convergent Dentalconvergentdental.com · United StatesConvergent Dental is a privately owned dental equipment and technology company.
Healthcare & Biotech
Portfolio page
Endogenexendogenex.com · United StatesEndogenex develops a system to treat type 2 diabetes using energy delivery in the small intestine to reset the body's metabolic signaling system
Healthcare & Biotech
Mar 2026Series C+Page + round
Enumera Molecularenumeramolecular.com · United StatesEnumera Molecular develops a rapid, low-cost molecular counting platform for clinical diagnostics.
Healthcare & Biotech
Portfolio page
http://www.esperion.com/esperion.com · United StatesEsperion Therapeutics, Inc. develops and commercializes cardiovascular disease therapies.
Healthcare & Biotech
Portfolio page
Flosonicsflosonicsmedical.com · United StatesFlosonics develops and markets a wireless, wearable ultrasound device for real-time hemodynamic assessments to clinicians
Healthcare & Biotech
Portfolio page
Francis Medicalfrancismedical.com · United StatesFrancis Medical develops therapies, including the Vanquish Water Vapor Ablation System, for treating prostate tissue
Healthcare & Biotech
Portfolio page
Inogeninogen.com · United StatesInogen produces and sells portable oxygen concentrators and other oxygen therapy equipment
Healthcare & Biotech
Portfolio page
Intellicytintellicyt.com · United States
Healthcare & Biotech
Portfolio page
JUMPCODE Genomicsjumpcodegenomics.com · United StatesThe company develops and sells products for genomic sequencing and analysis, including enzymes and kits for RNA depletion and DNA depletion.
Healthcare & Biotech
Portfolio page
Koyakoyamedical.com · United StatesKoya Medical develops and provides treatments for vascular health conditions, including edema and lymphedema.
Healthcare & Biotech
Portfolio page
Motif Neurotechmotifneuro.techMotif Neurotech builds neurotechnology to help monitor and regulate mental health and performance
Healthcare & Biotech
Portfolio page

About this data

site last read 5 Nov 2026
The homepage of Arboretum Ventures, as last read
arboretumvc.com as VCinfo last read it
Site
arboretumvc.com
Last read
5 Nov 2026
Watching since
6 Nov 2026
Rounds since
13 Aug 2025
Companies checked
32

Rates come from what VCinfo has observed since observation_start. Firms tend to remove companies that closed, so early rates understate reality. A company leaving a portfolio page does not mean it closed or exited. An unreachable site means our checks failed, nothing more.

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